Publications by authors named "Paweena Tunakhun"
Article Synopsis
- This study aims to improve the sensitivity of lateral-flow strips (LFSs) that use gold nanoparticles (AuNPs) to detect Neutrophil Gelatinase-Associated Lipocalin (NGAL) in urine samples.
- The researchers found that AuNPs with a diameter of 39.8 nm at pH 8 provided the best colorimetric signals for NGAL detection.
- Ultimately, the study enhances the diagnostic capabilities for early kidney injury detection by allowing reliable NGAL detection at as low as 12.5 ng/mL.
The incidence of kidney disease is increasing worldwide. Rapid and cost-effective approaches for early detection help prevent this disease. Neutrophil gelatinase-associated lipocalin protein (NGAL) is a novel biomarker for acute kidney injury (AKI) and chronic kidney disease (CKD).
View Article and Find Full Text PDFWe present a sensitive and selective lateral flow immunoassay (LFIA) for cotinine (COT), the primary metabolite of nicotine. COT is widely recognized as a superior biomarker to evaluate tobacco smoke exposure. The LFIA uses a competitive assay format where the COT-BSA capture competes with the target COT in urine samples for binding to the monoclonal antibody against COT (mAb-COT) conjugated with gold nanoparticles (mAb-COT-AuNPs).
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