Publications by authors named "Pavlos P Kafouris"
Article Synopsis
- The study investigated the relationship between lymphoma severity and cardiovascular health, specifically looking at arterial inflammation through FDG uptake in patients with active Hodgkin's and non-Hodgkin's lymphoma.
- Sixty-two chemotherapy-naïve patients were compared to previously treated lymphoma patients to assess metabolic tumor volume and glycolysis associated with arterial fluoride uptake.
- Results showed significant correlations between disease severity and arterial inflammation, with higher FDG uptake in active lymphoma patients compared to controls, particularly in advanced stages of the disease.
Background: Texture analysis has been increasingly used in the field of positron emission tomography (PET)/computed tomography (CT) imaging with Fluorine-18 fluorodeoxyglucose (18F-FDG), aiming at assessing tumor heterogeneity. The purpose of the present study is to examine the feasibility of performing texture analysis in carotid arteries, investigate the value of textural features as predictors of potential plaque vulnerability using as reference standards histological and immunohistochemical data and compare their performance with conventional uptake measurements.
Methods: 67 different 18F-FDG PET-based textural features were extracted from carotid images of 21 patients with high-grade carotid stenosis undergoing endarterectomy.
To develop and test a model predicting 2-deoxy-2-[F]fluoro-D-glucose ([F]FDG) standardized uptake value (SUV) changes over time in the aorta and the superior vena cava (SVC). Maximum aortic SUV and mean SVC SUV were determined at two time points (T1 and T2) in the ascending (ASC), descending (DSC), abdominal (ABD) aorta, aortic arch (ARC) and SVC of patients who have undergone [F]FDG PET/CT for clinical purposes. For SUV prediction at T2, linear and non-linear models of SUV difference for a given time change were developed in a derivation group.
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