[Transient neonatal hypothyrosis in premature neonates].

Plasma levels were measured of T4, free T4, T3, TSH in 64 premature neonates and in 41 those born at right time during the time-related course of the neonatal period. The results secured permit regarding the thyroid hypohormonosis syndrome in premature neonates as a consequence of the hypothalamic-hypophyseal-thyroid axis deficiency and of immaturity of the thyreostatic receptors as well. On the one hand, this promotes hypometabolism and, correspondingly, favours more economic utilization of bodily energy resources but on the other hand, such adaptation is not infrequently results in its failure and persistent thyrodeficiency, especially in very low-birth weight infants, during the whole of the neonatal period.

[Neurotic disorders in adolescents with vegetative dysfunction].

The main disorders in juveniles who are resident in the zone of small doses of ionizing radiation are vegetative dysfunctions. Of these, there prevail vegetovascular dysfunction comprising 45.7%, with neurocirculatory and vegetovisceral dysfunctions occurring less frequently (26.

[Structural and functional status of the hypophyseal-thyroid system in prenatally irradiated children].

In order to evaluate the morphologic-and-functional state of the hypophysis-thyroid system long after the Chernobyl accident we examined 1491 children from the northern territories of the Zhitomir region. Of these, 261 had not been in utero exposed to radioiodine, 1230 pediatric subjects proved to be postconception-exposed. In utero radioiodine has not been found to affect the thyroid size in any noticeable way.

[The mechanisms of diastolic dysfunction and their assessment by a Doppler method].

The Doppler method makes possible to reveal the relaxation disturbances and the increased left ventricular (LV) stiffness-pathophysiologic mechanisms of diastolic myocardial dysfunction (DMD), exerting opposite influence on the correlation of transmitral flow peaks. The decrease of the "diastolic reserve" in the patients with lung congestion is useful to diagnose DMD. But the type of LV filling, when the relative role of early diastole is decreased and of the late diastole-increased, cannot itself be recognized as pathologic.

[A biomechanical test of the rigidity of pin fixation in the root canals of human premolars and molars].

Three pin designs were under study: cone-like, with hatches, and snake-cranked. Fixation strength to rupture and compression of 1, 2, and 3 pins was examined. Snake-cranked pins were found best of all fixed in the root canal.

[The dimensions of the roots and root canals of human premolars and molars].

Dental roots and channels were measured in 160 premolars and molars on human upper and lower jaws. The longest roots were found in 5-th teeth and shortest in 7-th. The data suggest that dental channels can be extended up to 10 mm.

[Characteristics of neurohumoral regulation of water-electrolyte metabolism in premature newborn infants].

RIA was used to measure the level of beta 2-microglobulin, vasopressin, natriuretic factor, prostaglandin E2 and of the components of the renin-angiotensin-aldosterone system in full-term and premature neonates in the early neonatal period. In the first days of life, regulation of water-salt metabolism was discovered to be activated, especially in highly premature neonates. The early postnatal period is the critical period of ontogenesis where extreme tension of the neurohumoral systems may lead to the adaptation failure up to destabilization of the internal medium and grave metabolic disorders.

[State of the antioxidant system in premature newborn infants during early postnatal period].

The main parameters of the antioxidant system--AOS (glutathione peroxidase, glutathione reductase, superoxide dismutase, ceruloplasmin, estriol, estradiol) were studied in 58 normal full-term infants and in 178 premature infants in the course of the early neonatal period. In the control group, the functioning of the AOS appeared more perfect and was characterized by phasic changes in the course of the first week of life. The premature infants demonstrated functional disorganization of both enzymatic (glutathione in particular) and hormonal components of the system of antiperoxide defence.

[Role of breast feeding in the development of the function of the hypophyseal-adrenal system in newborn infants in the early neonatal period].

A radioimmunoassay was used for a study of ACTH, cortisol and aldosterone levels in the blood plasma of 96 infants and in breast milk. The plasma level of these hormones in the first days after delivery was high. A regular decrease in the level of the hormones was noted by the end of the early neonatal period.

[Effect of human milk enzymes on carbohydrate metabolism during adaptation of newborn infants in the early neonatal period].

The total activity and isoenzymatic composition of lactic dehydrogenase (LDG), malic dehydrogenase (MDG) and glucose 6-phosphate dehydrogenase (G-6-PDG) were studied in the blood serum and erythrocytes of 56 premature and 18 mature newborns, as well as in colostrum and mature breast milk. The growth of the role of anaerobic glycolysis was observed at the end of the neonatal period in the mature newborns. In highly premature newborns the activity of glycolysis and pentose cycle of glucose oxidation was especially high.

[Pylorus-sparing gastric resection in the surgical treatment of mediogastric ulcers].

Pylorus-preserving resections of the stomach were fulfilled in 118 patients with type I ulcers. The detected drop of the acid production in the stomach with ulcers of such localization was considered to be an indication to the removal of not more than 1/2 of the stomach. A necessary condition of pyloropreserving resection is the leaving of the pylorus zone not more than 2-3 cm.

[Role of natural feeding in providing newborn infants with progesterone].

The role of breast milk in the provision of the newborn with the sex hormone progesterone was studied. The radioimmunoassay was used to estimate the hormone content in the breast milk during lactation (87 samples) and in the blood plasma of 59 newborns. It was found that during the early postnatal period the progesterone level in the newborn's blood was gradually lowered.

[Role of breast feeding in providing the newborn infant with thyroid hormones].

Radioimmunoassay was conducted to study the content of triiodothyronine and thyroxine in the human milk and in the blood serum of mature and premature newborns. It was established that with the growth of the lactation period the content of triiodothyronine and thyroxine rose; it was, respectively, 0.5 +/- 0.