Plateau iris in children.

Narrow iridocorneal angles, a very rare condition in the pediatric population, can lead to visual loss through angle closure glaucoma. In the workup for patients with narrow iridocorneal angles, plateau iris must be considered in the differential diagnosis. We describe 5 children with plateau iris, the youngest 5 years of age.

Spectral-domain optical coherence tomography versus ultrasound biomicroscopy for imaging of nonpigmented iris tumors.

Purpose: To evaluate the use of spectral-domain optical coherence tomography (SDOCT) for imaging of nonpigmented iris tumors, through its comparison with ultrasound biomicroscopy (UBM).

Design: Retrospective observational case series.

Methods: Consecutive patients with non-pigmented iris tumors, not extending to the ciliary body, who were concurrently evaluated with SD-OCT and UBM were included.

Role of optical coherence tomography in verifying the specificity of ultrasonography in detecting subtle subretinal fluid associated with small choroidal melanocytic tumors.

Purpose: To report the use of optical coherence tomography (OCT) in verifying the specificity of the ultrasonographic "apical double echo" sign in detecting subtle subretinal fluid (SRF) associated with small choroidal melanocytic tumors.

Methods: Retrospective review of consecutive patients demonstrating ultrasonographic "apical double echo," indicative of subtle SRF, who concurrently underwent OCT on initial evaluation of untreated small choroidal melanocytic tumors. Ultrasonography was performed with eyecubed version 3, ophthalmic ultrasound system (Ellex/Innovative Imaging, Inc, Adelaide, Australia) and OCT with spectral-domain OCT, Cirrus HD-OCT, model 4000 (Carl Zeiss; Meditec, Dublin, CA).

Bilateral multifocal choroidal melanosis: a report of two cases.

Flat choroidal pigmented lesions have few differential diagnoses but encompass a wide range of clinical presentations. The authors report two cases of bilateral multifocal choroidal hyper-pigmented patches discovered in asymptomatic patients. Fluorescein angiography showed a normal pattern without blockage in the hyperpigmented areas with an otherwise normal choroidal vascular architecture.

Ultrasound biomicroscopy of the ciliary body in ocular/oculodermal melanocytosis.

Purpose: To describe the ultrasound biomicroscopy (UBM) findings of the ciliary body in patients with ocular/oculodermal melanocytosis.

Design: Retrospective observational case series study.

Methods: A retrospective chart and imaging database review was conducted for patients with unilateral ocular/oculodermal melanocytosis who underwent UBM examination at the Ocular Oncology Clinic of Princess Margaret Hospital.

Ultrasound biomicroscopy diagnosis of an axenfeld loop.

A 67-year-old man was referred for evaluation of a small mass on the sclera of the right eye. Ultrasound biomicroscopy of the mass suggested the diagnosis of Axenfeld loop.

Clinical and ultrasound biomicroscopy features associated with growth in iris melanocytic lesions.

Purpose: To determine the clinical and ultrasound biomicroscopy (UBM) features associated with growth in iris melanocytic lesions.

Study Design: Retrospective case series analysis.

Methods: We included all iris melanocytic lesions that were monitored between January 2005 and November 2009.

Intraocular extension of conjunctival invasive squamous cell carcinoma after pterygium surgery and cataract extraction.

Objectives: Conjunctival squamous dysplasia can often be confused with pterygium and pinguecula. Incomplete excision of dysplastic tissue can lead to recurrence and rarely intraocular invasion. This study describes two cases in which invasive squamous cell carcinoma (SCC) of the conjunctiva was originally partially resected as pterygium and eventually required enucleation for intraocular invasion.

Factors predictive of radiation retinopathy post (125)Iodine brachytherapy for uveal melanoma.

Objective: To report the host, tumour, and radiation-related predictive factors for developing radiation retinopathy post (125)Iodine brachytherapy for uveal melanoma.

Design: A retrospective clinical case series.

Participants: Three hundred consecutive patients with uveal melanoma treated with (125)Iodine brachytherapy.

Ultrasound biomicroscopy in the management of retinoblastoma.

Purpose: To determine the role of ultrasound biomicroscopy (UBM) in the management of children affected with retinoblastoma.

Methods: A review of clinical records of children with the diagnosis of retinoblastoma at the Hospital for Sick Children from January 1995 to December 2007, for whom UBM was used to determine the extent of intraocular tumor. Clinical characteristics were compared with UBM.

Ultrasound biomicroscopic imaging of iris melanoma: a clinicopathologic study.

Purpose: To demonstrate the correlation of ultrasound biomicroscopy (UBM) features of iris melanoma with histopathology.

Design: Retrospective analysis of medical records.

Methods: The medical records of patients that underwent surgery for iris melanoma at the Princess Margaret Hospital, University of Toronto, from June 1990 to October 1998 were reviewed.

Long-term follow-up of 42 patients with small ciliary body tumors with ultrasound biomicroscopy.

Purpose: To establish the growth behavior of small ciliary body tumors in a relatively large cohort of patients over an extended period.

Design: Retrospective, noncomparative case series.

Methods: Ciliary body tumors less than 4 mm in size within the penetration power of ultrasound biomicroscopy (UBM) were included.

Ultrasound biomicroscopic analysis of iris-sutured foldable posterior chamber intraocular lenses.

Purpose: To report ultrasound biomicroscopic (UBM) findings of iris-sutured foldable posterior chamber intraocular lenses (PCIOLs).

Design: Prospective, noninterventional consecutive case series.

Methods: Fifteen eyes with foldable acrylic IOL implantation using peripheral iris suture fixation in the absence of capsular support were included.

Management of iris melanomas with 125Iodine plaque radiotherapy.

Purpose: To report the experience of the Princess Margaret Hospital/University Health Network with the treatment of iris melanoma (IM) with (125)Iodine plaque brachytherapy.

Design: Retrospective noncomparative case series.

Methods: All cases of IM submitted to (125)Iodine plaque radiotherapy were included.

Management of ciliary body melanoma with iodine-125 plaque brachytherapy.

Objective: Because ciliary body melanoma often defies early diagnosis, and its treatment is controversial, we report our experience with the clinical presentation and management of ciliary body melanoma, treated with iodine-125 plaque brachytherapy.

Study Design: A retrospective noncomparative case series.

Participants: Forty-two patients with ciliary body melanoma treated with iodine-125 brachytherapy.

Anterior segment optical coherence tomography and ultrasound biomicroscopy in the imaging of anterior segment tumors.

Purpose: To evaluate the utility of anterior segment optical coherence tomography (OCT) in the imaging of anterior segment tumors and compare the images to ultrasound biomicroscopy (UBM).

Design: Prospective observational case series.

Methods: Eighteen eyes of 18 patients with anterior segment tumors were evaluated at Princess Margaret Hospital.

Ring melanoma of the ciliary body: clinical and ultrasound biomicroscopic characteristics.

Background: Diagnosis of ring melanoma is clinically difficult since the mass can remain hidden with standard slit-lamp biomicroscopy. The aim of this study was to evaluate the utility of ultrasound biomicroscopy (UBM) as a diagnostic tool for ring melanoma of the ciliary body.

Methods: This was a retrospective study of 6 eyes of 6 patients at Princess Margaret Hospital, Toronto, Ont.

A 100-200 MHz ultrasound biomicroscope.

The development of higher frequency ultrasound imaging systems affords a unique opportunity to visualize living tissue at the microscopic level. This work was undertaken to assess the potential of ultrasound imaging in vivo using the 100-200 MHz range. Spherically focused lithium niobate transducers were fabricated.