[Changes of lipoproteins during insulin therapy in diabetes mellitus type 1].

In well-controlled patients with type 1 diabetes mellitus, serum lipid and lipoprotein concentrations are similar to those in nondiabetic people. However, in poor glycaemic control, i.e.

[The role of insulin analogues in the current treatment of diabetes mellitus].

Introduction: Ever since insulin was discovered by Banting and Best in 1921, all further researches in this field had been conducted with one goal: to find new insulin molecules which would provide better glycemic control with fewer side effects i.e. to mimic endogenous physiological insulin secretion.

[Hashimoto's hypothyroidism associated with insulin resistance in type 2 diabetes].

INTRODUCTION Thyroid peroxidase activity inhibiting immunoglobulins (anti-TPO Ab) is a sign of autoimmune process in the thyroid gland. Association of hyperthyroidism and diabetes mellitus has been classically described. However, hypometabolic state, as a consequence of hypothyroidism, is not frequently linked with the biological activity of insulin.

[The role of autonomic cardiovascular neuropathy in pathogenesis of ischemic heart disease in patients with diabetes mellitus].

Introduction: Diabetes is strongly associated with macrovascular complications, among which ischemic heart disease is the major cause of mortality. Autonomic neuropathy increases the risk of complications, which calls for an early diagnosis. The aim of this study was to determine both presence and extent of cardiac autonomic neuropathy, in regard to the type of diabetes mellitus, as well as its correlation with coronary disease and major cardiovascular risk factors.