Publications by authors named "Pavitra Varaganti"
Recent Advances in Biomimetics for the Development of Bio-Inspired Prosthetic Limbs.
Biomimetics (Basel)
April 2024
Recent advancements in biomimetics have spurred significant innovations in prosthetic limb development by leveraging the intricate designs and mechanisms found in nature. Biomimetics, also known as "nature-inspired engineering", involves studying and emulating biological systems to address complex human challenges. This comprehensive review provides insights into the latest trends in biomimetic prosthetics, focusing on leveraging knowledge from natural biomechanics, sensory feedback mechanisms, and control systems to closely mimic biological appendages.
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- The folate receptor 1 (FOLR1) is a glycoprotein that helps transport folate in cells, primarily through receptor-mediated endocytosis, and is typically found in specific healthy tissues like the lung and kidney.
- In various solid tumors, particularly high-grade osteosarcoma, breast cancer, ovarian cancer, and non-small cell lung cancer, FOLR1 is often overexpressed, making it a promising target for cancer therapies and diagnostics.
- Recent advancements include the development of imaging agents that target FOLR1 for cancer detection, as well as folate-conjugated drugs designed to deliver treatment directly to cancer cells with high FOLR