Microplastics in packaged water, community stored water, groundwater, and surface water in rivers of Tamil Nadu after the COVID-19 pandemic outbreak.

The increased load of plastic in waste streams after the COVID-19 pandemic outbreak has increased the possibility of microplastics (MPs) contamination channelling through the rivers and infiltrating the aquatic ecosystems. MPs in packaged water, community-stored water, groundwater, and surface water of Kaveri River (KR), Thamirabarani River (TR), Adyar River (AR), and Cooum River (CR) in Tamil Nadu were therefore investigated about 2 years after the COVID-19 pandemic outbreak. Using μFTIR and μRaman spectroscopy, polyamide, polypropylene, polyethylene, ethylene vinyl alcohol copolymer resin, and polyvinyl chloride were identified as the primary polymer types.

Polyethylene terephthalate waste derived nanomaterials (WDNMs) and its utilization in electrochemical devices.

Plastics are a vital component of our daily lives in the contemporary globalization period; they are present in all facets of modern life. Because the bulk of synthetic plastics utilized in the market are non-biodegradable by nature, the issues associated with their contamination are unavoidable in an era dominated by polymers. Polyethylene terephthalate (PET), which is extensively used in industries such as automotive, packaging, textile, food, and beverages production represents a major share of these non-biodegradable polymer productions.

The next-generation DNA vaccine platforms and delivery systems: advances, challenges and prospects.

Vaccines have proven effective in the treatment and prevention of numerous diseases. However, traditional attenuated and inactivated vaccines suffer from certain drawbacks such as complex preparation, limited efficacy, potential risks and others. These limitations restrict their widespread use, especially in the face of an increasingly diverse range of diseases.

Silver diamine fluoride modified atraumatic restorative treatment compared to conventional restorative technique on carious primary molars-A randomized controlled trial.

Objective: To compare the success of silver diamine fluoride-modified atraumatic restorative technique (SMART) with that of the conventional drill and fill method in restoring carious lesions in primary molars.

Method: Children (4-8years old) reporting to a tertiary care hospital setting with asymptomatic cavitated dentinal carious lesions in primary molars were randomly allocated to two groups; SMART and Conventional; and subsequently restored with Glass Ionomer Cement (GIC). Follow-up evaluations were carried out by blinded independent evaluator at 6-months intervals to assess the status of restorations.

Investigation of thermal conductivity and thermal performance of heat pipes by structurally designed copolymer stabilized ZnO nanofluid.

The present study concentrated on estimating the thermal conductivity, stability, efficiency, and resistance of a heat pipe for heat exchangers, which were essential for many industrial applications. To achieve this, copolymer of amphiphilic poly (styrene-co-2-Acrylamido-2-methylpropane sulfonic acid) poly (STY-co-AMPS) was synthesized by free radical polymerisation technique. The dispersant were used for homogeneous solution and stabilization of ZnO nanofluids.

Multi-spectroscopic, calorimetric and molecular dynamics evaluation on non-classical intercalation of antiviral drug Molnupiravir with DNA.

The interaction of an antiviral drug Molnupiravir () with calf thymus DNA (CT-DNA) was investigated using a series of biophysical techniques. A significant hyperchromism with a blue shift  nm in the UV-Vis spectra indicated a high binding affinity of for CT-DNA with binding constants in the order of 10 M. Competitive fluorescent dye displacement assays with ethidium bromide (EB) and Hoechst 33258 suggested an intercalative mode of binding of with CT-DNA.

A review on biological biohydrogen production: Outlook on genetic strain enhancements, reactor model and techno-economics analysis.

Modernisation of industrial and transportation sector would have not imaginable without the help of fossil fuels, but constant usage has led to many environmental concerns. As a step forward, for safer next generation living we are forced to look into green fuels like bio‑hydrogen and higher alcohols. This review mainly focuses on bio‑hydrogen production via biological pathways, genetic improvements, knowledge gap, economics, and future directions.

Multi-spectroscopic and molecular simulation methods of analysis to explore the mode of binding of Mebendazole drug with calf-thymus DNA.

UV-vis, fluorescence, circular dichroism (CD) and H NMR spectroscopic techniques have been employed to explore the mode of binding of Mebendazole (MBZ) drug with calf thymus DNA (CT-DNA). UV-vis and fluorescence spectral studies suggested a complex formation between the drug and nucleic acid. The fluorescence of MBZ was found to enhance upon binding with CT-DNA through a ground state complex formation with K in the order of 10 M.

Mercury sources, contaminations, mercury cycle, detection and treatment techniques: A review.

Mercury is considered a toxic pollutant harmful to our human health and the environment. Mercury is highly persistent, volatile and bioaccumulated and enters into the food chain, destroying our ecosystem. The levels of mercury in the water bodies as well as in the atmosphere are affected by anthropogenic and natural activities.

Development and validation of a RP-UPLC method for the determination of betamethasone dipropionate impurities in topical formulations using a multivariate central composite design.

The current study presents a specific, accurate, simple, and rapid UPLC method for the determination of impurities present in cream and ointment formulations of betamethasone dipropionate (BMD). The analytical method was optimized using central composite design (CCD) prior to the method validation. Critical Process Parameters (CPPs) and Critical Quality Attributes (CQAs) were identified for the analytical method.

Phenolic fraction extracted from Kedrostis foetidissima leaves ameliorated isoproterenol-induced cardiotoxicity in rats through restoration of cardiac antioxidant status.

In this study, the cardioprotective effects of partially purified phenolic fraction of Kedrostis foetidissima leaves (PFK) were evaluated in isoproterenol (ISO)-induced myocardial infarction rat model. ISO induction to experimental rats for two consecutive days significantly increased the levels of triglycerides, cholesterol, phospholipids, free fatty acids, low-density lipoproteins, and cardiac biomarker enzymes, and decreased the levels of high-density lipoproteins and antioxidant enzyme activity. Pretreatment of experimental rats with PFK for 45 days led to a significant elevation in antioxidant enzyme activity.

A Review on Phytochemistry, Pharmacological Action, Ethanobotanical Uses and Nutritional Potential of Kedrostis foetidissima (Jacq.) Cogn.

Nature is an amazing source for food, shelter, clothing and medicine. An impressive number of modern drugs are isolated from many sources like plants, animals and microbes. The development of natural products from traditional medicines is of great importance to society.

Profiling of anthocyanins and carotenoids in fruit peel of different colored mango cultivars.

Mango cultivars are broadly categorized into green, yellow, and red types based on their peel colors. Anthocyanins and carotenoids are the most important pigments responsible for the color of fruits. The information available on the composition of pigments on mango peel was scanty, and the exact role of anthocyanins and carotenoids in imparting peel color was not clear.

Vegetables' juice influences polyol pathway by multiple mechanisms in favour of reducing development of oxidative stress and resultant diabetic complications.

Objective: Hyperglycemia induced generation of free radicals and consequent development of oxidative stress by polyol pathway is one of the crucial mechanisms stirring up development of diabetic complications. We evaluated influence of ten vegetables' juice on polyol pathway along with their antioxidant and antioxidative stress potentials.

Materials And Methods: Aldose reductase activity was determined utilising goat lens and human erythrocytes.