Publications by authors named "Pavel Stanimirov"
Oral cavity stem cells (OCSCs) have been the focus of intense scientific efforts due to their accessibility and stem cell properties. The present work aims to compare the different characteristics of 6 types of dental stem cells derived from the oral cavity: dental pulp stem cells (DPSC), stem cells from human exfoliated deciduous teeth (SHED), periodontal ligament stem cells (PDLSC), stem cells from the apical papilla (SCAP), bone marrow mesenchymal stem cells (BMSC), and gingival mesenchymal stem cells (GMSC). Using immunofluorescence and real-time polymerase chain reaction techniques, we analysed the cells for stem cell, differentiation, adhesion, and extracellular matrix markers; the ability to proliferate in vitro; and multilineage differentiation potential.
View Article and Find Full Text PDFIntroduction: Rhino-orbito-cerebral mucormycosis has been reported as a sequela after coronavirus disease in immunocompromised patients with poorly controlled diabetes mellitus. Most cases have been identified in India, with only 19 reported elsewhere.
Methodology: We herein report the results of clinical, imaging, microbiological, and histopathological studies in an immunocompetent 67-year-old male with rhino-orbital infection by Finegoldia magna and Mucorales molds following severe SARS-CoV-2 disease associated with new-onset decompensated diabetes mellitus.
Introduction: The full decontamination and disinfection of the root canal system is essential for the success of regenerative endodontic procedures. The current literature does not have information regarding mechanical cleaning of immature teeth with contemporary endodontic instuments.
Aim: To compare the thickness and volume of the dentin removed from the roots of immature teeth after endodontic preparation using XP-endo Finisher, GentleFile Brush and a standard H-file scraping technique through micro-computed tomography.
Article Synopsis
- FGF8 is a special protein that helps tooth development by guiding tooth cells to where teeth grow.
- Researchers tested how FGF8 can help adult tooth cells heal and grow stronger.
- The study found that FGF8 boosts the growth and healing of tooth cells and may help them do their job better in making teeth.
Objective: To describe and provide a comprehensive overview on the development, use and efficacy of autologous platelet concentrates in different in vitro and in vivo studies focusing on oral and maxillofacial pathologies.
Materials And Methods: Present work employs an extensive critical overview of the literature on the development and application of platelet concentrates.
Results: Platelet concentrates are innovative endogenous therapeutic agents which gained a lot of interest in different medical and dental disciplines due to their potential ability to stimulate and increase regeneration of soft and hard tissues.