Publications by authors named "Pavel Shandra"
Article Synopsis
- Lacosamide (LCM) is an anticonvulsant that may work well with other antiepileptic drugs (AEDs), so this study aimed to investigate those potential interactions using isobolographic analysis.
- The research involved testing LCM in combination with other AEDs like carbamazepine and lamotrigine in mice, evaluating both seizure control and effects on motor coordination.
- Findings revealed that LCM showed synergistic effects when combined with certain AEDs and did not enhance adverse effects, suggesting it could be an effective add-on therapy for patients with difficult-to-treat epilepsy.
