Publications by authors named "Pavan Suryadevara"
Objective: Ketamine and esketamine have been used in the field of psychiatry to alleviate conditions such as major depressive disorder. Our objective was to evaluate the current literature on the use of ketamine for symptoms of social withdrawal in autism spectrum disorder (ASD) and autism-like conditions.
Methods: A comprehensive search of PubMed and Web of Science was conducted to identify literature involving the use of ketamine to treat symptoms of autism and social withdrawal.
Article Synopsis
- The HPA axis is disrupted in obesity, leading to leptin resistance in the brain and issues with noradrenergic function in DIO rats.
- Metformin treatment in these rats resulted in decreased weight gain, fat mass, and improved HPA axis activity by normalizing its functions and reducing corticotropin-releasing hormone levels.
- The study highlights metformin's potential to address HPA axis dysfunction in obesity, suggesting a new therapeutic role for the drug in managing weight.