Postural Disharmony Causing Myofacial Pain: A Case Report and Review of Literature of the Treatment.

Myofacial pain, a chronic painful condition of muscle origin, has numerous precipitating factors, if undiagnosed or left untreated could lead to compromised function and poor quality of life. In this case report, a female patient giving a history of 10 years of pain in the head and neck region was eventually diagnosed with myofacial pain secondary to bowing posture. The patient was successfully treated with combination of treatment modalities (TENS therapy, exercises, occlusal splint, etc.

In silico evaluation of drugs used in treatment of oral lichen planus.

Background: Oral lichen planus (OLP) is a chronic T cell-mediated, immunological, mucocutaneous disease with a number of genes and inflammatory mediators implicated in its pathogenesis. Heart shock protein 70 and the proinflammatory mediator TNFα have been predominantly involved in the etiopathogenesis of oral lichen planus.

Methods: In this study, the action of 27 commonly used drugs for treating OLP at HSP70 and TNFα were evaluated by molecular docking using Maestro Schrodinger version 10.

Spectrum of features in Darier's disease: A case report with emphasis on differential diagnosis.

Oral genodermatoses includes a spectrum of inherited dermatological disorders with varying oral mucosal manifestations. Darier's disease is an autosomal dominant disorder with defect in desmosomal attachment. This case report presents oro cutaneous manifestations of Darier's disease in a 40 year old female patient with a detailed review on etiology, pathogenesis, differential diagnosis and management of the condition.

Association of OLP and thyroid disorder: Case report and review of literature.

Oral lichen planus is a chronic T cell mediated inflammatory condition with multifactorial etiology. Being autoimmune mediated condition, it has been associated with other autoimmune disorders. This case report discusses the possible presentation of oral lichen planus in hypothyroid patients as a marker of severity of the thyroid deficient status and the possible pathogenetic link between both the conditions.

Clinical evaluation of photodynamic therapy for the treatment of refractory oral Lichen planus - A case series.

Oral lichen planus (OLP) is a chronic inflammatory, immune mediated mucocutaneous disorder of uncertain etiology. Psychologic stress has been found to be a main contributing factor in onset and progression of lesions. Most erosive OLP patients are refractory to available therapies, even corticosteroids, and report remarkable side effects.

Intravenous injection of elemental mercury: A report of two cases.

Two cases of intravenous injection of elemental mercury are described in this report. One patient succumbed and the other remains asymptomatic two years after the surgical removal of all the injected mercury. Management of intravenous injection of elemental mercury (intended to be an aphrodisiac in these two cases) is discussed here and the need for surgical removal of all accessible mercury has been emphasized.

Twenty years' follow-up of a de-epithelialised turnover flap.

The authors have used the de-epithelialised turnover flap (Thatte's Flap) for covering compound defects over the tendo-achilles in 31 patients in the period covering 1980-2000. Two of these patients have come up for follow-up after 20 years. In this late follow-up, the results are good and the tendon which was bridged by the dermis of the flap is functioning to allow the patients to stand on their toes.

Rhythm in acetylcholine-acetylcholinesterase system in the slug, Laevicaulis alte (Ferussac, 1821).

Acetylcholine (ACh) and acetylcholinesterase (AChE) in central nervous system (CNS) and foot muscle (FM) of Laevicaulis alte cresting at 0400 h under LD 12:12 (0600 to 1800 : 1800 to 0600 h) regimen are in phase with each other. Nuli hypothesis (Ho) than for FM AChE, was rejected (A not equal to 0) since F (2,3) (0.05) greater than 9.

Rhythmic succinate dehydrogenase activity in the slug, Laevicaulis alte (Ferussac, 1821).

Succinate dehydrogenase (SDH) in central nervous system (CNS) and food muscle (FM) crested at 0400 h while in midgut gland (MG) it was out of phase. The average enzyme level (in per cent) was high during dark h half cycle (data points at 2000, 0000 and 0400 h) in CNS and FM and opposition prevailed for MG. Null hypothesis (Ho) was accepted (Ho = A = O) for CNS and rejected (Ho = A not equal to O) for MG and FM.