Publications by authors named "Pauwels I"

Additional and refurbished pumping stations are required to mitigate the intensifying occurrence of droughts and floodings. These installations negatively impact threatened freshwater fish populations due to the increased risk of injury and mortality when fish pass through them. Fish-friendly pumping installations have been proposed as a potential solution to reduce these risks.

View Article and Find Full Text PDF

Antimicrobial resistance (AMR) is a global problem that results in high morbidity and mortality, particularly in low- and middle-income countries. Inappropriate use of antimicrobials is a major driver of AMR. This study aimed to evaluate the rate and quality of antimicrobial prescription and use at the University Teaching Hospital of Kigali (CHUK), a tertiary-referral teaching hospital.

View Article and Find Full Text PDF

Diadromous fish species are characterised by spawning migrations between freshwater and marine environments, where they traverse through estuaries and close to coasts. This species group has declined substantially over the past decades due to anthropogenic effects such as habitat fragmentation and loss and overfishing. A rising potential threat to their population recovery is the increasing installation of subsea power cables (SPCs) which generate electromagnetic fields (EMF) as they transport energy from offshore wind farms to land.

View Article and Find Full Text PDF

Background: The Global Point Prevalence Survey (PPS) of antimicrobial consumption and resistance has been widely undertaken to combat the global threat of antimicrobial resistance (AMR). This study was conducted in alignment with the Global-PPS in three tertiary care hospitals in Kerman, Iran, to evaluate antimicrobial consumption patterns.

Methods: The study was conducted from January 2020 to January 2021 in Afzalipour, Shafa, and Shahid Bahonar Hospitals.

View Article and Find Full Text PDF

Background: Antibiotic use during pregnancy is widespread with notable variations across regions.

Methods: This systematic review and meta-analysis (Prospero protocol CRD42023418979) examines the prevalence and variability of antibiotic use in pregnancy globally and regionally, considering different methodologies and maternal characteristics. We searched Embase, PubMed, and Web of Science for observational studies published in English from the year 2000 and onwards.

View Article and Find Full Text PDF

Introduction: point prevalence surveys have been used as a standardized tool to monitor antibiotic consumption to inform antimicrobial stewardship interventions in many countries. The 2021 WHO model list of Essential Medicines has classified antibiotics into three groups: access, watch and reserve. The aim of this paper is to describe the antibiotics used within a space of three years between 2018 and 2021 at the University of Uyo Teaching Hospital based on WHO AWaRe classification.

View Article and Find Full Text PDF
Article Synopsis
  • The study assessed antimicrobial prescribing patterns in children and neonates at three hospitals in Sanandaj, Iran, comparing the data to benchmarks from Southeast Asia and Europe.
  • In Sanandaj, a significantly higher percentage of patients received antimicrobials (74.9% in neonates) compared to Southeast Asia (56.9%) and Europe (28.6%), with common misuse of broad-spectrum antibiotics like ceftriaxone and prolonged usage for surgical prophylaxis.
  • The findings highlight an urgent need for improved antibiotic stewardship programs in Sanandaj to address the high rates of empirical prescribing and enhance diagnostic capabilities.
View Article and Find Full Text PDF

Many fish species depend on migration for various parts of their life cycle. Well-known examples include diadromous fish such as salmon and eels that need both fresh water and salt water to complete their life cycle. Migration also occurs within species that depend only on fresh water.

View Article and Find Full Text PDF

Background: Migration is a vital element of the life cycle of many freshwater fish species but is increasingly hampered globally by riverine barriers. Fish passes are a common approach to enable migration past barriers but are often ineffective. More knowledge is required on fish behaviour as they approach barriers such as habitat preferences.

View Article and Find Full Text PDF

Background: Fish migration has severely been impacted by dam construction. Through the disruption of fish migration routes, freshwater fish communities have seen an incredible decline. Fishways, which have been constructed to mitigate the problem, have been shown to underperform.

View Article and Find Full Text PDF

The global presence of plastic litter and its accumulation in the environment has become an issue of concern to the public and policymakers. This concern has triggered innovators in past decades to design and develop a multitude of remediation technologies to prevent plastic from entering the environment, or to clean up legacy litter. This study aims to (i) systematically review the current scientific literature on plastic remediation technologies, (ii) create a 'plastic clean-up and prevention overview' illustrating 124 remediation technologies and 29 characteristics, (iii) qualitatively analyse their key characteristics (e.

View Article and Find Full Text PDF

River fragmentation is an increasing issue for water managers and conservationists. Barriers such as dams interfere with freshwater fish migration, leading to drastic population declines. While there are a range of widely implemented mitigation approaches, e.

View Article and Find Full Text PDF

The COVID-19 pandemic is a global public health challenge with understudied effects on antimicrobial usage. We aimed to analyze antimicrobial prescribing patterns in COVID-19 patients in Russian multi-field hospitals by means of the Global-PPS Project developed by the University of Antwerp. Out of 999 patients in COVID-19 wards in six hospitals surveyed in 2021, 51.

View Article and Find Full Text PDF

Background: The global point prevalence survey (Global-PPS) is the standard for the surveillance of prescribed antimicrobials among inpatients and provides data for the development of hospital antimicrobial stewardship programs.

Aim: To evaluate the prevalence and quality of antimicrobial prescriptions using the universally standardized Global-PPS protocol in a non-acute care hospital in Saitama Prefecture, Japan.

Methods: Antimicrobial prescriptions for inpatients, staying at the hospital overnight, were surveyed on three separate week days in November 2018, January 2019, and May 2019.

View Article and Find Full Text PDF

Understanding animal movement is essential to elucidate how animals interact, survive, and thrive in a changing world. Recent technological advances in data collection and management have transformed our understanding of animal "movement ecology" (the integrated study of organismal movement), creating a big-data discipline that benefits from rapid, cost-effective generation of large amounts of data on movements of animals in the wild. These high-throughput wildlife tracking systems now allow more thorough investigation of variation among individuals and species across space and time, the nature of biological interactions, and behavioral responses to the environment.

View Article and Find Full Text PDF

Current mitigation strategies to offset marine plastic pollution, a global concern, typically rely on preventing floating debris from reaching coastal ecosystems. Specifically, clean-up technologies are designed to collect plastics by removing debris from the aquatic environment such as rivers and estuaries. However, to date, there is little published data on their potential impact on riverine and estuarine organisms and ecosystems.

View Article and Find Full Text PDF

Background: Patient-level surveillance of antimicrobial use (AMU) in Canadian hospitals empowers the reduction of inappropriate AMU and was piloted in 2017 among 14 hospitals in Canada. We aimed to describe AMU on the basis of patient-level data in Canadian hospitals in 2018 in terms of antimicrobial prescribing prevalence and proportions, antimicrobial indications, and agent selection in medical, surgical and intensive care wards.

Methods: Canadian adult, pediatric and neonatal hospitals were invited to participate in the standardized web-based cross-sectional Global Point Prevalence Survey of Antimicrobial Consumption and Resistance (Global-PPS) conducted in 2018.

View Article and Find Full Text PDF

Background: The Global Point Prevalence Survey of Antimicrobial Consumption and Resistance (Global-PPS) provides a methodology to support hospitals worldwide in collecting antimicrobial use data. We aim to evaluate the impact of the Global-PPS on local antimicrobial stewardship (AMS) programmes and assess health care professionals' educational needs and barriers for implementing AMS.

Methods: A cross-sectional survey was disseminated within the Global-PPS network.

View Article and Find Full Text PDF
Article Synopsis
  • * The survey found that 50% of patients were prescribed antimicrobials, primarily from the WHO 'Access' and 'Watch' categories, with a notable lack of 'Reserve' antibiotics and common use for prophylaxis in obstetric and gynecological surgeries.
  • * The G-PPS led to the establishment of antimicrobial stewardship interventions, including AMS committees and training, to improve prescription practices, but continuous monitoring through repeat surveys and broader participation is necessary
View Article and Find Full Text PDF

Background: Indiscriminate antimicrobial use is one of the greatest contributors to antimicrobial resistance. A low level of asepsis in hospitals and inadequate laboratory support have been adduced as reasons for indiscriminate use of antimicrobials among surgical patients. At present, there are no guidelines for presumptive antibiotic use in Nigeria and sub-Saharan Africa.

View Article and Find Full Text PDF

Objectives: Optimising antimicrobial prescribing in hospitals through antimicrobial stewardship (AMS) is essential in addressing the global threat of antimicrobial resistance. The objective of this study was to evaluate the impact of a hospital-wide programme, delivered by a multidisciplinary AMS team, on antimicrobial prescribing outcomes.

Methods: The AMS programme consisted of a combination of persuasive, restrictive, and structural components and was implemented in two phases.

View Article and Find Full Text PDF

Objectives: The WHO Access, Watch and Reserve (AWaRe) classification has been developed to support countries and hospitals in promoting rational use of antibiotics while improving access to these essential medicines. We aimed to describe patterns of worldwide antibiotic use according to the AWaRe classification in the adult inpatient population.

Methods: The Global Point Prevalence Survey on Antimicrobial Consumption and Resistance (Global-PPS) collects hospital antibiotic use data using a standardized PPS methodology.

View Article and Find Full Text PDF
Article Synopsis
  • * Out of 13,595 patients surveyed, 26.14% received antimicrobials, primarily third-generation cephalosporins, and compliance with hospital antibiotic guidelines varied over the three studies, ranging from 66.8% to 74.8%.
  • * The study highlighted issues such as low documentation rates for treatment indications and stop dates, high rates of prolonged perioperative antibiotic use, and insufficient targeted therapy, suggesting a need for tailored antimicrobial stewardship programs in hospitals.
View Article and Find Full Text PDF

Background: In the majority of familial breast cancer (BC) families, the etiology of the disease remains unresolved. To identify missing BC heritability resulting from relatively rare variants (minor allele frequency ≤ 1%), we have performed whole exome sequencing followed by variant analysis in a virtual panel of 492 cancer-associated genes on BC patients from BRCA1 and BRCA2 negative families with elevated BC risk.

Methods: BC patients from 54 BRCA1 and BRCA2-negative families with elevated BC risk and 120 matched controls were considered for germline DNA whole exome sequencing.

View Article and Find Full Text PDF

Introduction: An early acquired or congenital absence of sensory input of the vestibule will lead to severe delayed posturomotor milestones. Previous studies have proven modifications and even complete ipsilateral loss of vestibular function after unilateral cochlear implantation. The objective of this study was to evaluate whether sequential cochlear implantation has an impact on vestibular function.

View Article and Find Full Text PDF