Publications by authors named "Paulose Thomas"

The study includes a conductometric chemical sensor design using aligned MnO nanorods. Nanostructuring is an emerging field of prominence due to its capacity to introduce unprecedented properties in materials with potential applications. A hydrothermally prepared in situ MnO sample appears with an urchin rod-like morphology, which changes to a spherical shape upon annealing.

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The incidence and prevalence of end-stage renal disease (ESRD) is increasing. Diabetic nephropathy has increased in absolute numbers and as a proportion of patients with ESRD. This is almost totally accounted for by the explosive outbreak of Type 2 diabetes mellitus (DM).

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Ketoconazole inhibits cytochrome P 3A4, leading to a 10-fold increase in sirolimus blood levels. Although it has not been reported in the clinical setting so far, sirolimus and ketoconazole co-prescription can lead to cost saving by reducing the dose of sirolimus administered. After informed consent was obtained, sirolimus and ketoconazole co-prescription was studied in six patients who could not afford the current recommended doses.

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Background: GB virus C/hepatitis G virus (GBV-C/HGV) and TT virus (TTV) have been widely reported in patients with high parenteral risk such as haemodialysis and renal transplant recipients. The occurrence of these agents in association with hepatitis B virus (HBV) and hepatitis C virus (HCV), in Indian renal transplant recipients, is yet unreported.

Study Design: Molecular and serological markers of GBV-C/HGV and TTV were examined in addition to those for HBV, HCV and hepatitis D virus (HDV) in a selected group of seventy renal transplant recipients.

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Background: The epidemiology of nocardiosis in the tropics among renal transplant recipients has not been reported.

Methods: An evaluation of nocardiosis for 30 yr in one of the large transplant centres in South Asian region.

Results: Of the 1968 patients who received primary renal allografts at Christian Medical College & Hospital, 27 patients developed nocardiosis over 30 yr.

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