Epidemiological and Radiomorphometric Aspects of the Accessory Mental Foramen in Brazilian Individuals: An Analysis by Cone Beam Computed Tomography.

Background: The accessory mental foramen is characterized by small foramina in the surrounding area of the mental foramen with communication with the mandibular canal. The aim of this research was to evaluate epidemiological and radiomorphometric aspects of the accessory mental foramen (AMF) using cone beam computed tomography (CBCT) in Brazilian individuals.

Material And Methods: This was a cross-sectional, quantitative, retrospective descriptive study with 250 CBCT scans of dentate individuals in the anterior mandibular region, aged between 18 and 69 years.

Analysis of microvascular density and collagen structure of the medial meniscotibial ligament of the knee: Immunohistochemical study with CD31 and histology with Picrosirius red.

Background: The aim of the present study was to describe the structure of the collagen matrix and the microvascularization of the medial meniscotibial ligament (MMTL), in order to contribute to the refinement of the surgical technique for repairing these structures and consequently lead to a reduction in the risk of anterior cruciate ligament re-rupture.

Methods: Twelve MMTLs were obtained from deceased organ donors. The ligaments were initially analyzed macroscopically and evaluated histologically using hematoxylin and eosin staining.

Computed tomography assessment of neurocranial structures for sexual dimorphism identification: a meta-analysis.

The human neurocranium exhibits significant sexual dimorphism, making it a valuable resource for anthropological studies. This systematic review aggregated and analyzed data from literature on sex differences in neurocranial dimensions as measured by computed tomography (CT). Following registration of the review protocol with PROSPERO (#CRD 42023442451), comprehensive searches were conducted in six databases and gray literature.

Preemptive vs preventive coadministration of ibuprofen L-arginine and dexamethasone in lower third molar surgeries: a randomized controlled trial.

Objective: To compare the effect of different preemptive and preventive analgesia strategies involving oral coadministration of ibuprofen-arginine (770 mg)-Ib-Ar and dexamethasone (8 mg)-DX, and their respective placebos (P-Ib-Ar and P-DX), four evaluation groups on inflammatory and laboratory parameters, impact on quality of life, pain catastrophizing perception and sleep quality related after lower third molar surgery.

Study Design: A randomized split-mouth, triple-blind, controlled clinical trial was conducted with 48 volunteers. They were allocated depending on the use of Ib-Ar or DX, 1 hour before surgery or immediately postoperatively, discriminating the groups: G1 (Ib-Ar + DX), G2 (Ib-Ar + P-DX), G3 (P-Ib-Ar + DX), and G4 (P-Ib-Ar + P-DX).

PI3K/AKT Immunoexpression Influences the Prognostic Factors of Patients Diagnosed with Oropharyngeal Squamous Cell Carcinoma.

Background: Squamous cell carcinoma (SCC) is the most common histological type in the oropharynx with high incidence and mortality. The Pi3K-AKT signaling pathway is important for understanding prognostic factors such as metastasis, which is involved in the aetiopathogenesis of cancer and is associated with angiogenesis, progression, and cell survival. The aim of this study was to evaluate the correlation of the Pi3K/AKT pathway with prognostic factors associated with oropharyngeal SCC, including overall survival.

Evaluation of Tissue Biocompatibility of Calcium Silicate-based and Epoxy Resin-based Sealers.

Introduction: Calcium silicate-based sealers are an alternative to be used into root canal, mainly to their biological properties. However, some biological parameters need to be determined in an animal research model. So, the aim of the present study was to evaluate the tissue biocompatibility of a calcium silicate-based sealer (EndoSequence BC Sealer) and an epoxy resin-based sealer (AH-Plus).

Clinical and radiographic success of pulpotomy and pulpectomy in primary and permanent teeth: a Systematic Review and Meta-Analysis.

Background: This systematic review evaluated the long-term clinical effectiveness of Biodentine in vital pulp therapy procedures.

Material And Methods: Two independent reviewers searched the PubMed, Scopus, Web of Science, Cochrane, LILACS, and DOSS databases for articles published until August 2023. Review Manager and GRADEpro software were used for the analysis, and the Revman5.

Pterygopalatine disjunction-associated SARME and the nasal cavity - A systematic literature review.

Background: This study aimed to evaluate the effect of surgically assisted rapid maxillary expansion (SARME) with pterygopalatine disjunction (PD) on the nasomaxillary complex structures.

Material And Methods: A systematic two-phase review, recorded in the PROSPERO database, was conducted. Search strategies were performed using PubMed, Scopus, Web of Science, COCHRANE, LILACS and DOSS databases, including gray literature (Open Grey, Google Scholar, and ProQuest).

Host repair polymorphisms and H. pylori genes in gastric disease outcomes: Who are the guardian and villains?

Gastric cancer (GC) is the fourth-leading cause of cancer-related mortality. The intestinal subtype of GC comes after the cascade of Correa, presenting H. pylori infection as the major etiological factor.

Effectiveness of trans-sinus dental implants in the complete arch rehabilitation of the edentulous maxilla: A systematic review and meta-analysis.

Statement Of Problem: Systematic reviews to determine the effectiveness of oral rehabilitation with trans-sinus dental implants in patients with an atrophic maxilla are lacking.

Purpose: The purpose of this systematic review was to determine the effectiveness of trans-sinus dental implants installed in patients with an atrophic maxilla.

Material And Methods: Searches were conducted in 5 databases including the nonpeer-reviewed literature up to March 2024 by 2 independent reviewers according to established inclusion and exclusion criteria and according to the question: Can trans-sinus implants be a suitable option for the rehabilitation of the atrophic maxilla? The meta-analysis was carried out using the Revman software program for the variables implant loss and marginal bone loss using a 95% confidence interval.

Digoxin attenuates bisphosphonate related osteonecrosis of the jaws by RORγt-dependent Th17 response in male rats.

Objective: The study aimed to evaluate digoxin, an RORγt inhibitor, in Medication-Related Osteonecrosis of the Jaws (MRONJ) in male rats treated with zoledronic acid (ZA).

Study Design: Forty male Wistar rats were divided into a negative control group (0.1 mL/kg saline), a positive control group (ZA, 0.

Impact of L-PRF on pain and healing outcomes in lower third molar surgery: a randomized split-mouth trial.

This study explored the effects of L-PRF on pain, soft tissue healing, periodontal condition, and post-extraction bone repair of mandibular third molars (3Ms). A randomized, prospective, triple-blind, split-mouth clinical trial was conducted with 34 volunteers. Eligible patients were randomly allocated into two treatments: G1 (without L-PRF), G2 (alveoli filled with L-PRF), in which the removal of bilateral 3Ms was performed at the same surgical time.

Time series and risk factors associated with mortality in women with cervical cancer from 2000 to 2021.

Introduction: Cervical cancer is a significant public health problem worldwide. The development of cervical neoplasms is associated with persistent infection by oncogenic subtypes of the HPV virus, which are responsible for around 70% of cervical cancers.A study carried out in Brazil between 2002 and 2021 recorded 133,429 deaths from cervical cancer.

Risk Factors associated with noncarious cervical lesions.

Background: Noncarious cervical lesions (NCCLs) is the dental structure loss unrelated to caries. The aim was to investigate the possible relationship between bruxism, age, gender, daily routine and dietary habits and NCCL, and correlate with sensitivity and position in the dental arch.

Material And Methods: 245 patients aged between 18 and 40 participated in the survey, in which a questionnaire focused on parafunctional habits, erosion, abrasion, dental abfraction and acidic diet was conducted.

Naltrexone accelerated oral traumatic ulcer healing and downregulated TLR-4/NF-kB pathway in Wistar rats.

Objective: To assess the effect of naltrexone on oral mucosal healing using a traumatic ulcer model DESIGN: Wistar rats (n = 112) received distilled water (control) or naltrexone (0.5, 10, or 50 mg/kg/day). Ulcers were induced on the buccal mucosa using a round skin biopsy punch (diameter 6 mm).

Evaluation of pathogenic variants detected in high homology regions of the gene. How effective is long-range PCR?

Introduction: Lynch syndrome (LS) is an inherited cancer predisposition syndrome characterized by a high risk of colorectal and extracolonic tumors. Germline pathogenic variants (GPV) in the gene are associated with <15% of all cases. The pseudogene presents high homology with , challenging molecular diagnosis by next-generation sequencing (NGS).

Mapping trends in preemptive analgesia related to oral surgery with the use of Ibuprofen: a comprehensive quantitative and qualitative analysis of bibliometric parameters.

Purpose: This study aims to conduct a thorough analysis, both quantitative and qualitative, of bibliometric parameters related to preemptive analgesia (PA) in oral surgical procedures (OSP).

Methods: Research trends on PA in OSP using ibuprofen were reviewed through bibliometric analysis of 68 journal articles published from 1991 to 2022 in the Web of Science database. Bibliometric indicators were applied to analyze the journal article data, including the annual distribution of publications and literature growth, document types, citation indicators to measure qualitative research performance, and keyword mapping to identify research trends.

Tropane Alkaloid Isolated from Erythroxylum bezerrae Exhibits Neuropharmacological Potential in an Adult Zebrafish (Danio rerio) Model.

This study carried out to investigate the anti-inflammatory and antinociceptive effect of tropane alkaloid (EB7) isolated from E. bezerrae. It evaluated the toxicity and possible involvement of ion channels in the antinociceptive effect of EB7, as well as its anti-inflammatory effect in adult zebrafish (Zfa).

Salivary immunoglobulin levels and periodontal indices in Brazilian children with and without type 1 diabetes.

This cross-sectional study evaluated the association between salivary immunoglobulins, plaque index, and gingival index in Brazilian children with and without type 1 diabetes mellitus (DM1). The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist for the reporting of observational studies was followed. The DM1 group had 38 children, and an equal number of volunteers matched by sex and age were recruited as controls.