Diagnosis of viral infectious diseases through sensitive detection of human serum antibodies using a modified label-free electrochemical biosensor.

Rapid virus identification is crucial for preventing outbreaks. The COVID-19 pandemic has highlighted the critical nature of rapid virus detection. Here, we designed a label-free electrochemical biosensor modified with gold nanoparticles (AuNPs) to detect IgG antibodies from human serum, enabling rapid point-of-care diagnostics.

Greener production of a starch-based nanohybrid material (core-shell) for the simultaneous extraction of persistent organic pollutants in shrimp samples.

Here, a novel nanohybrid material (Ag@CD@ANS) based on oat starch was produced, characterized, and applied to extract persistent organic pollutants in a shrimp sample. By the characterization experiments, Ag@CD@ANS was successfully synthesized. The functionalization of the material by 1,2-naphthoquinone-4-sulphonic acid (ANS) was confirmed using the infrared technique and CHN elemental analysis.

Molecularly imprinted polymer as sorbent phase for disposable pipette extraction: A potential approach for creatinine analysis in human urine samples.

Traditionally, creatinine determination is made by a spectrophotometric method; however, some compounds present in biological samples can interfere with creatinine determination, decreasing the sensitivity of the method in urine samples. Consequently, we report the development of a new molecularly imprinted polymer as a sorbent phase for disposable pipette extraction to determine creatinine in urine samples by high-performance liquid chromatography with UV detection. The synthesized polymer showed a high superficial area and presented a first-order kinetic reaction and a high selectivity for creatinine extraction compared to the non-molecularly imprinted polymer.

Polyester-toner electrophoresis microchips with improved analytical performance and extended lifetime.

This paper reports the fabrication of polyester-toner (PT) electrophoresis microchips with improved analytical performance and extended lifetime. This has been achieved with a better understanding about the EOF generation and the influence of some parameters including the channel dimensions (width and depth), the injection mode, and the addition of organic solvent to the running buffer. The analytical performance of the PT devices was investigated using a capacitively coupled contactless conductivity detector and inorganic cations as model analytes.