Publications by authors named "Paulo Sergio Chaib"

Background: Advanced megaesophagus predisposes to risks of malnutrition infections and cancer, in addition to having a significant impact on quality of life. There is currently no consensus in the literature regarding the best surgical option for advanced megaesophagus, although there is a predilection for esophagectomy, despite this surgery being associated with significant morbidity and mortality. Other surgical procedures, such as esophageal mucosectomy and Heller cardiomyotomy, have been proposed with good results.

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Article Synopsis
  • CVID is a rare immunodeficiency disorder that often has intermittent symptoms, making it hard to diagnose in both children and adults, and it's commonly associated with gastrointestinal and respiratory issues.
  • The case of a 38-year-old man illustrates how his diagnosis of CVID was delayed for 19 years due to overlooked symptoms like diarrhea and recurrent infections, which only led to testing after significant complications arose.
  • Serum protein electrophoresis (SPE) is an affordable and accessible test that can help identify CVID by detecting low gamma globulin levels, but it's often not used in the initial evaluation of patients with diarrhea or recurrent infections.
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