Attomolar sensitivity of a redox capacitive and DNA-receptive interface attained by quantum-rate signal amplification concept.

This study demonstrates the application of quantum capacitance (C) methods to develop highly sensitive genosensors. This is achieved by employing the quantum mechanical rate (ν∝e/hC) concept to enhance the signal response of a redox-active, DNA-receptive interface. In these DNA-receptive interfaces, electrons are transported through the redox-tagged component, enabling signal amplification by adding a redox probe to the sample containing the target DNA.

On the fundamentals of quantum rate theory and the long-range electron transport in respiratory chains.

It has been shown that both the electron-transfer rate constant of an electrochemical reaction and the conductance quantum are correlated with the concept of quantum capacitance. This simple association between the two separate concepts has an entirely quantum rate basis that encompasses the electron-transfer rate theory as originally proposed by Rudolph A. Marcus whether statistical mechanics is appropriately taken into account.

Quantum rate dynamics and charge screening at the nanoscale level.

It has been demonstrated that quantum-rate electrodynamics originate from charged quantum states within redox moieties coupled to electrodes. In this study, we demonstrate that this phenomenon is not restricted to redox reactions, and that it is applicable to certain charge screening conditions that depend on electron-ion pairing phenomena. Quantum-rate electrodynamics governs the dynamics of charged inorganic semiconductor states at the nanoscale level.

Ab Initio QM/MM Simulation of Ferrocene Homogeneous Electron-Transfer Reaction.

Here, we demonstrate the feasibility of hybrid computational methods to predict the homogeneous electron exchange between the ferrocene and its oxidized (ferrocenium) state. The free energy for ferrocene oxidation was determined from thermodynamic cycles and implicit solvation strategies within density functional theory (DFT) methods leading to no more than 15% of deviation (in the range of 0.1-0.

Electron transfer and conductance quantum.

The electron transfer rate constant of an electrochemical reaction and the conductance quantum are fundamental concepts that drive processes ranging from nanoscale electronic circuits to photosynthesis. In this paper, it is demonstrated that they are correlated with the concept of electrochemical capacitance. The relationship between electron transfer rate, quantum transport and electrochemical capacitance encompasses the theory of electron transfer rate proposed by Rudolph A.

Comparing glucose and urea enzymatic electrochemical and optical biosensors based on polyaniline thin films.

Analytical sensors that can detect chemical (including biological) analytes are becoming increasingly widespread within the field of analytical chemistry. More than this, in a world tending towards the 'internet-of-things', the miniaturization of such devices is becoming increasingly urgent. Accordingly, electrochemical methods that are simultaneously multiplexable and effective at a miniature scale are receiving much attention.

INSEL: an in silico method for optimizing and exploring biorecognition assays.

A practical in silico method for optimizing and exploring biointeraction-based events is developed.

Quartz crystal microbalance as a tool for kinetic enzymatic assays by variation of pH.

In this work, it is shown that the quartz crystal microbalance (QCM) can be a powerful and simple tool for quick and precise kinetic enzymatic assays. This is shown by measuring immobilized acetylcholinesterase (AChE) activity with variations of pH as a case study.

Changeover during in situ compositional modulation of hexacyanoferrate (Prussian Blue) material.

This paper describes the importance of (H2O)6 clusters in controlling the properties of hexacyanoferrate (Prussian Blue) materials. A careful in situ study of compositional changes by using electrogravimetric techniques (in ac and dc modes) in hexacyanoferrates containing K+ alkali metals reveals the existence of a changeover in the properties of these films in a narrow potential range. Control of the compositional variation of the changeover is dependent on the K+ stoichiometric number in the compound structure.