Publications by authors named "Paulo R Einloft"

Article Synopsis
  • The study aimed to translate, adapt culturally, validate, and test the reliability of the EMPATHIC-30 questionnaire for Brazilian parents of children discharged from the PICU.
  • The translation followed best practices, resulting in a total content validity coefficient above the accepted average, indicating strong content relevance.
  • Reliability testing showed varying results across different domains, with the overall internal consistency being excellent at 0.90, confirming the instrument's reliability for future use in assessing parental empowerment in intensive care settings.
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Background: Because of its high prevalence and negative impact on quality of life and longevity, overweight in childhood and adolescence is a major public health concern. The objective of the present study was to determine whether excess weight is associated with clinical outcomes in critically ill children and adolescents admitted to the pediatric intensive care unit (PICU).

Method: This retrospective cohort study was performed with children and adolescents admitted to a PICU over 3 years.

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Article Synopsis
  • - This study aimed to assess serum ferritin levels measured within 48 hours of hospital admission as a predictor of mortality in pediatric sepsis patients, highlighting a significant link between ferritin levels and adverse outcomes.
  • - Conducted at a tertiary care hospital in South America, it included 350 children aged 6 months to 18 years diagnosed with sepsis, identifying a 40.3% prevalence of iron deficiency anemia among them.
  • - Findings revealed that higher serum ferritin levels correlated with increased mortality rates, with a notable 10-fold increase in ferritin associated with five times the risk of mortality, indicating that ferritin can be a valuable prognostic marker in this setting.
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Article Synopsis
  • The study aimed to assess whether measuring cerebrospinal fluid (CSF) ferritin levels can help diagnose purulent meningitis (PM) in children.
  • Researchers analyzed 81 children suspected of having meningitis, measuring CSF ferritin levels and comparing results across three diagnostic groups: PM, aseptic meningitis (AM), and no meningitis.
  • Findings showed significantly higher CSF ferritin levels in children with PM compared to those with AM or no meningitis, suggesting that CSF ferritin could serve as a valuable biomarker for diagnosing PM in affected children.
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Objective: To estimate the workload and size the nursing team using the scales TISS-28 and NEMS in a pediatric intensive care unit.

Methods: An observational prospective study with a quantitative approach was conducted at the pediatric intensive care unit of a university hospital from Jan 1st, 2009 to Dec 31st, 2009. All children who remained hospitalized for more than 8 hours were included, with length of stay of 4 hours in case of death.

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Article Synopsis
  • The study aimed to explore how echocardiogram results, ferritin levels, C-reactive protein, and leukocyte counts relate to poor outcomes in pediatric sepsis patients.
  • A prospective cohort study included children aged 28 days to 18 years who had sepsis and required prolonged mechanical ventilation and vasoactive drugs; key indicators were measured over 72 hours.
  • Results showed that higher ferritin levels and signs of cardiac dysfunction were linked to longer hospital stays, more extended mechanical ventilation, and a higher inotropic agent usage, indicating worse health outcomes for the patients.
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Objective: To describe the characteristics and the outcome of infants with acute viral bronchiolitis submitted to mechanical ventilation.

Methods: We performed a retrospective study enrolling all infants (less than 12 months old) admitted with the diagnosis of acute viral bronchiolitis and submitted to mechanical ventilation in an university affiliated Brazilian pediatric intensive care unit between March, 2004 and September, 2006 (3 consecutives winters). The mechanical ventilation parameters' employed on 1st, 2nd, 3rd, 7th day and before extubation were evaluated as well as the evolution (mortality rate, presence of acute respiratory distress syndrome and the prevalence of complications).

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Objective: Vasopressin is a neuropeptide hormone which has been used clinically for more than 50 years and plays a major role in circulatory homeostasis and in the regulation of serum osmolality. Recent work has emphasized its role in the treatment of septic shock. This paper reviews the physiology of this neurohormone and the available evidence in favor of its use as a vasodilator for children in shock.

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Objective: To describe the serum cortisol profile and evaluate the adrenal response in children with septic shock, and determine the influence of these factors on the outcome and mortality in this group.

Methods: Between May and November 2003, 22 children with septic shock admitted to two pediatric intensive care units in southern Brazil were followed. Adrenal function was evaluated based on the levels of cortisol measured on the occasion of the diagnosis of septic shock and on the response of serum cortisol 30 min after the administration of intravenous corticotrophin (0.

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Objective: To compare the performance of the PRISM (Pediatric Risk of Mortality) and the PIM (Pediatric Index of Mortality) scores at a general pediatric intensive care unit, investigating the relation between observed mortality and survival and predicted mortality and survival.

Methods: A contemporary cohort study undertaken between 1 June 1999 and 31 May 2000 at the Pontifícia Universidade Católica do Rio Grande do Sul, Hospital São Lucas pediatric intensive care unit. The inclusion criteria and the PRISM and PIM calculations were performed as set out in the original articles and using the formulae as published.

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Objectives: To study the possible change on mode of deaths, medical decision practices, and family participation on decisions for limiting life-sustaining treatments (L-LST) over a period of 13 yrs in three pediatric intensive care units (PICUs) located in southern Brazil.

Methods: A cross-sectional study based on a retrospective chart review (1988 and 1998) and on prospective data collection (from May 1999 to May 2000).

Setting: Three PICUs in Porto Alegre, southern Brazilian region.

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Objective: To review epidemiological data from patients admitted to a Pediatric Intensive Care Unit (PICU), Brazil, and to compare them to medical aspects associated to disease severity and mortality. Also, to profile these patients, including demographic data, disease prevalence, mortality rates and associated factors.

Methods: Retrospective data were collected from all patients admitted in a PICU of a university hospital between 1978 and 1994.

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