Introduction: Missing values occur in nearly all clinical studies, despite the best efforts of the investigators, and cause frequently unrecognised biases. Our aims were (1) to assess the reporting and handling of missing values in the critical care literature; (2) to describe the impact of various techniques for handling missing values on the study results; (3) to provide guidance on the management of clinical study analysis in case of missing data.
Methods: We reviewed 44 published manuscripts in three critical care research journals.
Am J Respir Crit Care Med
November 2009
Rationale: Many sources of conflict exist in intensive care units (ICUs). Few studies recorded the prevalence, characteristics, and risk factors for conflicts in ICUs.
Objectives: To record the prevalence, characteristics, and risk factors for conflicts in ICUs.