Publications by authors named "Paulo Alosilla Sandoval"
Article Synopsis
- Early enteral nutrition via feeding tubes is crucial for managing severe acute pancreatitis (SAP), with nasojejunal tubes traditionally preferred for assumed benefits.
- This study compared the safety and efficacy of enteral feeding using nasogastric versus nasojejunal tubes in SAP patients through a meta-analysis of four randomized controlled trials (RCTs) involving 192 patients.
- Results showed no significant difference in all-cause mortality or secondary outcomes between the two feeding methods, indicating nasogastric feeding is similarly effective and safe, but more extensive and well-designed trials are necessary for confirmation.
Article Synopsis
- PTID accounts for around 5% of primary gastrointestinal tumors, with varying histological types showing both benign and malignant characteristics.
- A study analyzed 45 patients, primarily diagnosed at an average age of 54.2 years, with most cases (86%) found in the jejunum; GISTs, lymphomas, and adenocarcinomas were the most common tumor types identified.
- Double-balloon enteroscopy served as the primary diagnostic and treatment method, supporting various endoscopic procedures for managing these tumors, including biopsies and surgical interventions.
Unlabelled: The management of inflammatory bowel disease (IBD) is mainly medical, however, more than 70% of patients with Crohn's disease (CD) and 25% with ulcerative colitis (UC) will require surgery during their lifetime.
Objective: To evaluate medical, surgical management and evolution in patients with moderate-to-severe IBD.
Materials And Methods: Observational, descriptive, retrospective study from January 2011 to December 2019 in the Gastroenterology Service of the Guillermo Almenara Irigoyen National Hospital, Lima-Peru.
Unlabelled: Epithelioid granuloma is a characteristic histological feature of Crohn's disease (CD), but their significance with respect to the severity and progression of the disease is still uncertain.
Objective: To evaluate the clinical characteristics of CD patients in relation to the presence or not of granulomas in histological findings.
Materials And Methods: An observational, descriptive, retrospective study in patients diagnosed with CD from January 2004 to December 2019 in the gastroenterology department of the Guillermo Almenara Irigoyen National Hospital, Lima-Peru.
Article Synopsis
- - Crohn's disease (CD) is a serious, long-lasting inflammation of the digestive system that is becoming more common in Latin America, severely affecting patients' quality of life.
- - A study at a major hospital in Lima, Peru, analyzed 55 CD patients, revealing that the average age of diagnosis was about 56 years, with common symptoms including abdominal pain and weight loss.
- - Key findings included a mix of disease locations and types, predominantly treated with corticosteroids and anti-TNF therapies; about one-third of patients required surgery, and there was a 5.4% mortality rate in the cohort.
[Clinical-pathological characteristics and endoscopic management of colonic sessile serrated lesions in a reference hospital in Lima - Peru].
Rev Gastroenterol Peru
August 2021
Unlabelled: Colorectal cancer (CRC) is one of the most frequent worldwide. Approximately one third of cases originate from the serrated pathway of carcinogenesis, with colonic sessile serrated lesions (SSL) being the main cause of interval CRC.
Objective: To evaluate the clinical, endoscopic, histological characteristics and endoscopic management of colonic LSS.
[Loss of response to anti-TNF therapy in inflammatory bowel disease: experience in a reference hospital in Lima - Peru].
Rev Gastroenterol Peru
April 2021
Objective: To evaluate the response to treatment with anti-TNFs in patients with inflammatory bowel disease.
Materials And Methods: Prospective observational study conducted in the Gastroenterology service of the Guillermo Almenara National Hospital, from January 2015 to August 2018.
Results: 31 patients with inflammatory bowel disease who received maintenance therapy with Infliximab were evaluated.
Unlabelled: Ulcerative colitis is a chronic inflammatory disease characterized by a recurrent and remitting course. Clinical remission and mucosal healing are the current therapeutic goals in management. The histological remission could be a better objective because of its prognostic impact.
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