Effectiveness of two-drug therapy versus monotherapy as initial regimen in hypertension: A propensity score-matched cohort study in the UK Clinical Practice Research Datalink.

Purpose: To compare the effectiveness on blood pressure (BP) of initial two-drug therapy versus monotherapy in hypertensive patients.

Methods: Using the Clinical Practice Research Datalink, linked with Hospital Episode Statistics and Office for National Statistics, we identified a cohort of adults with uncontrolled hypertension, initiating one or two antihypertensive drug classes between 2006 and 2014. New users of two drugs and monotherapy were matched 1:2 by propensity score.

Association of perception of front-of-pack labels with dietary, lifestyle and health characteristics.

Objective: To identify patterns of perception of front-of-pack (FOP) nutrition labels and determine dietary, lifestyle and health profiles related to such patterns.

Design: Cross-sectional.

Participants/setting: 28,952 French adults participating in the web-based Nutrinet-Santé cohort.

Perception of front-of-pack labels according to social characteristics, nutritional knowledge and food purchasing habits.

Objective: To identify patterns of perception of front-of-pack (FOP) nutrition labels and to determine social factors, nutritional knowledge and attention to packaging features related to such patterns.

Design: Cross-sectional. Perception was measured using indicators of understanding and acceptability of three simple FOP labels (the 'Green Tick', the logo of the French Nutrition and Health Programme (PNNS logo) and 'simple traffic lights' (STL)) and two detailed formats ('multiple traffic lights' (MTL) and the 'colour range' logo (CR)).

Socio-economic, demographic, lifestyle and health characteristics associated with consumption of fatty-sweetened and fatty-salted foods in middle-aged French adults.

Few studies have specifically focused on characteristics associated with consumption of combined fatty-salted and fatty-sweetened foods, whereas their identification could be useful for defining effective public health measures. The aim of the present study was to investigate the association between demographic, socio-economic, lifestyle and health characteristics and consumption of these types of food in a general sample of French adults. Dietary intake was assessed using a minimum of six 24 h dietary records collected over a 2-year period in 6240 subjects aged 35-60 years who participated in the Supplémentation en VItamines Minéraux et AntioXydants cohort study.