Publications by authors named "Pauline Leroux"

Article Synopsis
  • * Researchers analyzed data from 361 infants with confirmed pertussis, finding that 32 (9%) developed fulminant symptoms, which were more common in neonates, unvaccinated, and premature infants.
  • * Results indicated that B. pertussis strains that produced PRN were associated with higher risks of fulminant pertussis, suggesting the significance of PRN in the severity of the disease.
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Article Synopsis
  • Bordetella pertussis, the bacteria causing whooping cough, continues to circulate globally despite vaccines, and this study focuses on differences between two fimbrial serotypes, FIM2 and FIM3.
  • The research involved analyzing the microbial traits and protein profiles of 19 bacterial isolates, revealing that FIM2 produces more fimbriae and biofilm but is less effective at agglutination and survival in cord blood than FIM3.
  • Findings indicate that distinct fimbrial serotypes and their clades are linked to significant differences in virulence factors, which could affect disease spread and prevention strategies.
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Objectives: Hemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening condition affecting young children. It is potentially triggered by Epstein-Barr virus (EBV). This study describes the neuroradiological features observed in 75 children with genetically confirmed primary HLH, comparing EBV-induced with non-EBV-induced HLH forms.

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