Publications by authors named "Pauline Kerneves"
Article Synopsis
- * Distinguishing cHCL from similar conditions like variant hairy cell leukemia (vHCL) and splenic diffuse red pulp lymphoma (SDRPL) can be difficult, particularly since some cHCL patients may not express typical markers or mutations.
- * A study involving deep sequencing found that 93% of cHCL patients had mutations, with some showing clonal evolution; notably, certain mutations were linked to poorer outcomes, suggesting a need for careful monitoring and
Hairy cell leukemia (HCL) is characterized by abnormal villous lymphoid cells that express CD103, CD123, CD25 and CD11c. HCL-like disorders, including hairy cell leukemia variant (vHCL) and splenic diffuse red pulp lymphoma (SDRPL), have similar morphologic criteria and a distinct phenotypic and genetic profile. We investigated the immunophenotypic features of a large cohort of 82 patients: 68 classical HCL, 5 vHCL/SDRPL and 9 HCL-like NOS.
View Article and Find Full Text PDF