Methylome Response to Proteasome Inhibition by Virulence Factor Syringolin A.

DNA methylation is an important epigenetic mark required for proper gene expression and silencing of transposable elements. DNA methylation patterns can be modified by environmental factors such as pathogen infection, in which modification of DNA methylation can be associated with plant resistance. To counter the plant defense pathways, pathogens produce effector molecules, several of which act as proteasome inhibitors.

Gamete-specific epigenetic mechanisms shape genomic imprinting.

Although most genes are expressed equally from both parental alleles, imprinted genes are differentially expressed depending on their parental origin. In flowering plants, imprinting depends on DNA methylation. Conversely, activation of the expressed allele requires DNA demethylation.