Publications by authors named "Pauline Desdemoustier"
Article Synopsis
- - Malaria continues to be a significant global health issue, worsened by the increasing resistance of the parasites to current treatments, prompting the search for new antimalarial options, particularly from plants known for their alkaloid content.
- - A study screened 43 methanolic extracts from 28 plant species, revealing 12 extracts with promising antiplasmodial activities, confirming previous findings and uncovering new potential treatments.
- - The use of advanced molecular networking techniques identified unknown alkaloids potentially effective against malaria, highlighting the importance of ongoing research into these plants for future drug development.
is an endemic tree from the Mascarene Islands that belongs to the Anacardiaceae family. The leaves of this plant were phytochemically studied previously, and isolated alkyl cyclohexenone derivatives, poupartones A - C, demonstrated antiplasmodial and antimalarial activities. In addition to their high potency against the , high toxicity on human cells was also displayed.
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