Nephrol Dial Transplant
February 2020
Background: The development of an artificial glomerular unit may be pivotal for renal pathophysiology studies at a multicellular scale. Using a tissue engineering approach, we aimed to reproduce in part the specific glomerular barrier architecture by manufacturing a glomerular microfibre (Mf).
Methods: Immortalized human glomerular cell lines of endothelial cells (GEnCs) and podocytes were used.