Publications by authors named "Pauline Berthe"

Article Synopsis
  • The study aimed to analyze the risk of major adverse cardiovascular events (MACE) in patients with atopic dermatitis (AD) who are treated with Janus kinase inhibitors (JAKi), as previous data linked JAKi use to cardiovascular issues in other inflammatory diseases.* -
  • A systematic review and meta-analysis were conducted, examining multiple databases for relevant studies, which included cohorts of patients aged 12 and older, revealing a total of 9,309 in the 'controlled-period' cohort and 9,118 in the 'all-JAKi' cohort.* -
  • The findings indicated that among the 23 selected studies, patients had been treated with various JAKi drugs, including baricitinib and upad
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Joint symptoms associated with gout, mostly characterized by joint flare-ups, are well known. Tophi represent the main cutaneous manifestation of gout, most often associated with a chronic and inadequately controlled disease. On rare occasions, atypical skin manifestations may occur.

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Introduction: Atopic dermatitis (AD) is a highly prevalent, chronic, inflammatory skin disease. Several orally administered Janus kinase inhibitors (JAKis, including baricitinib, upadacitinib and abrocitinib) have received a marketing authorisation for AD.Clinical trials in rheumatoid arthritis (RA) have flagged up a potential risk of JAKi-induced venous thromboembolic events (VTEs).

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