Publications by authors named "Paulina Skrzeszewska"

Article Synopsis
  • Violacein is a purple pigment from bacteria that shows a lot of promise due to its biological properties, but it's not very water-soluble, making it tricky to study.
  • This study investigates how Janthinobacterium lividum uses extracellular vesicles (EVs) to transport violacein, finding that these EVs were more effective in producing and delivering the compound than traditional methods.
  • The research suggests that J. lividum EVs can successfully deliver violacein to human cells, specifically targeting melanoma, which opens up new possibilities for cancer treatment.
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The melting properties of various triblock copolymers with random coil middle blocks (100-800 amino acids) and triple helix-forming (Pro-Gly-Pro)(n) end blocks (n = 6-16) were compared. These gelatin-like molecules were produced as secreted proteins by recombinant yeast. The investigated series shows that the melting temperature (T(m)) can be genetically engineered to specific values within a very wide range by varying the length of the end block.

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In this article we study shape-memory behavior of hydrogels, formed by biodegradable and biocompatible recombinant telechelic polypeptides, with collagen-like end blocks and a random coil-like middle block. The programmed shape of these hydrogels was achieved by chemical cross-linking of lysine residues present in the random coil. This led to soft networks, which can be stretched up to 200% and "pinned" in a temporary shape by lowering the temperature and allowing the collagen-like end blocks to assemble into physical nodes.

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