Publications by authors named "Paulina Sanchez Castro"

Objective: Evidence from low- and middle-income countries regarding the effect of smoking in people with diabetes is lacking. Here, we report the association of smoking with mortality in a large cohort of Mexican adults with diabetes.

Methods: Participants with diabetes mellitus (self-reported diagnosis, use of antidiabetic medications or HbA1c ≥ 6.

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Background: Prediabetes has been associated with increased all-cause and cardiovascular mortality. However, no large-scale studies have been conducted in Mexico or Latin America examining these associations.

Methods: We analyzed data from 115,919 adults without diabetes (diagnosed or undiagnosed) aged 35-84 years who participated in the Mexico City Prospective Study between 1998 and 2004.

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Article Synopsis
  • The study estimates the prevalence of four diabetes subgroups in Mexico using data from national health surveys conducted between 2016 and 2022, focusing on over 23,000 adults.
  • The overall diabetes prevalence was found to be 16.04%, with specific subgroup prevalence rates highlighting that severe insulin-deficient diabetes (SIDD) and obesity-related diabetes (MOD) are more common in Southern Mexico, while age-related (MARD) and severe insulin-resistant diabetes (SIRD) are prevalent in Northern Mexico and Mexico City.
  • Factors such as social disadvantage and speaking an indigenous language were associated with increased odds for SIDD, indicating regional and sociodemographic disparities that could impact diabetes management in Mexico.
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  • Post-acute sequelae after SARS-CoV-2 infection (PASC) affects 12.44% of adults in Mexico, with fatigue and pain being the most reported symptoms.
  • Analysis of 24,434 participants from the 2022 Mexican National Health and Nutrition Survey revealed higher PASC prevalence linked to reinfections, depressive symptoms, and lower social status.
  • Vaccination and infections during the Omicron variant surge correlated with a reduction in severe PASC cases, emphasizing the need for preventive measures and booster vaccinations.
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Article Synopsis
  • A study analyzed prediabetes prevalence trends in Mexico from 2016 to 2022 using different definitions (ADA, WHO, IEC) after excluding known diabetes cases.
  • The overall prevalence of prediabetes in 2022 was 20.9%, showing a downward trend for certain definitions, while HbA1c-based definitions indicated an increase, especially among adults over 40 and those with other risk factors.
  • The findings suggest that, despite some decreases in certain prediabetes criteria, there is still a rising concern related to cardiometabolic conditions linked to prediabetes in Mexico.
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