Prediction of Young׳s modulus of trabeculae in microscale using macro-scale׳s relationships between bone density and mechanical properties.

According to the literature, there are many mathematical relationships between density of the trabecular bone and mechanical properties obtained in macro-scale testing. In micro-scale, the measurements provide only the ranges of Young׳s modulus of trabeculae, but there are no experimentally tested relationships allowing the calculation of the distribution of Young׳s modulus of trabeculae within these experimental ranges. This study examined the applicability of relationships between bone density and mechanical properties obtained in macro-scale testing for the calculation of Young׳s modulus distribution in micro-scale.