Publications by authors named "Paulina Gach"
Article Synopsis
- Tick-borne encephalitis virus (TBEV) causes severe brain inflammation, primarily in northern Asia and Europe, and can lead to chronic illness or death; climate change is expanding its reach.
- Interferon-induced transmembrane proteins (IFITMs), particularly IFITM3, are crucial for inhibiting TBEV infection and preventing cell death caused by the virus, with studies employing CRISPR-Cas9 methods confirming their protective roles.
- Despite their protective effects, TBEV may partially evade IFITM suppression during high-density infections by spreading directly between cells, highlighting the need for further research into antiviral strategies and innate immune responses.
J Mater Sci Mater Med
July 2018
Article Synopsis
- Bioprosthetic heart valves have clinical success but face limitations; tissue-engineering techniques offer a promising alternative.
- The study investigates how different storage conditions affect the biomechanics and morphology of pulmonary valves used for acellular scaffold preparation.
- Findings reveal that storage at 4°C results in increased tissue stiffness and altered viscoelastic properties, indicating that storage conditions significantly influence acellularization efficiency and the mechanical properties of heart valve tissues.
