Publications by authors named "Paulina Cortes"

Article Synopsis
  • The study evaluated clinical practice guidelines for managing depression globally, focusing on their development and implementation quality.
  • It found that guidelines from low- and middle-income countries generally had less transparency, fewer multidisciplinary authors, and lower rates of systematic reviews compared to those from high-income countries.
  • The conclusion emphasizes the need for improved planning, reporting, and measurement of guideline effectiveness, especially in low- and middle-income countries, and recommends that future guidelines include strategies for implementation and assessment.
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Objective: Literature about journal clubs in postgraduate psychiatry programs is scarce, and there is no reference to residents' preferences.

Methods: Residents were asked to respond to a survey about their general satisfaction with the current journal club format and paper preferences, according to subject, scope, and type.

Results: Residents' general satisfaction was high.

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The title compound, C(15)H(22)O(4), consists of two trans-fused six-membered rings and a trans-fused five-membered γ-lactone. The ep-oxy and hydroxyl groups are α-oriented. The cyclo-hexane rings adopt half-chair and chair conformations and the lactone ring is in an envelope conformation.

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The mammalian kidney bumetanide-sensitive Na(+)-K(+)-2Cl(-) and thiazide-sensitive Na(+)-Cl(-) cotransporters are the major pathways for salt reabsorption in the thick ascending limb of Henle's loop and distal convoluted tubule, respectively. These cotransporters serve as receptors for the loop- and thiazide-type diuretics, and inactivating mutations of corresponding genes are associated with development of Bartter's syndrome type I and Gitleman's disease, respectively. Structural requirements for ion translocation and diuretic binding specificity are unknown.

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