Bull World Health Organ
October 2020
Objective: Literature about journal clubs in postgraduate psychiatry programs is scarce, and there is no reference to residents' preferences.
Methods: Residents were asked to respond to a survey about their general satisfaction with the current journal club format and paper preferences, according to subject, scope, and type.
Results: Residents' general satisfaction was high.
Acta Crystallogr Sect E Struct Rep Online
July 2009
The title compound, C(15)H(22)O(4), consists of two trans-fused six-membered rings and a trans-fused five-membered γ-lactone. The ep-oxy and hydroxyl groups are α-oriented. The cyclo-hexane rings adopt half-chair and chair conformations and the lactone ring is in an envelope conformation.
View Article and Find Full Text PDFThe mammalian kidney bumetanide-sensitive Na(+)-K(+)-2Cl(-) and thiazide-sensitive Na(+)-Cl(-) cotransporters are the major pathways for salt reabsorption in the thick ascending limb of Henle's loop and distal convoluted tubule, respectively. These cotransporters serve as receptors for the loop- and thiazide-type diuretics, and inactivating mutations of corresponding genes are associated with development of Bartter's syndrome type I and Gitleman's disease, respectively. Structural requirements for ion translocation and diuretic binding specificity are unknown.
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