Publications by authors named "Paulina Bitkowska"
The primary pleural neoplasms constitute around 10% of the pleural tumors. The currently recommended method for their imaging is CT which has been shown to have certain limitations. Strong development of the MRI within the last two decades has provided us with a number of sequences that could potentially be superior to CT when it comes to the pleural malignancies' detection and characterization.
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- The study focuses on the gene that produces the oncoprotein CIP2A, which is linked to cancer development and has increased expression in multiple myeloma (MM) and other cancers.
- Researchers analyzed the impact of a specific genetic variation (rs2278911, 686C > T) in 128 newly diagnosed MM patients using blood samples.
- Results indicated that the TT genotype of this SNP, along with factors like thrombocytopenia and certain disease characteristics, was associated with shorter progression-free and overall survival, suggesting its potential as a diagnostic tool for identifying high-risk patients.
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- Lung cancer is the leading cause of cancer-related deaths globally, often diagnosed late due to limited diagnostic methods, which worsens patient outcomes.
- There is growing interest in using microRNAs (miRNAs) as early diagnostic tools, which may help detect non-small-cell lung cancer (NSCLC) before symptoms appear, potentially improving clinical outcomes.
- Some studies show that miRNA levels could predict treatment responses in NSCLC, suggesting that analyzing and adjusting these levels might enhance treatment effectiveness.
The immune system plays a key role in cancer suppression. Immunotherapy is widely used as a treatment method in patients with various types of cancer. Immune checkpoint blockade using antibodies, such as anti-PD-1, anti-PD-L1, and anti-CTLA-4, is currently gaining popularity.
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