Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER).

Background: The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) was a multicenter randomized controlled trial that reported beneficial effects on cognition for a 2-year multimodal intervention (diet, exercise, cognitive training, vascular risk monitoring) versus control (general health advice). This study reports exploratory analyses of brain MRI measures.

Methods: FINGER targeted 1260 older individuals from the general Finnish population.

The Effect of Multidomain Lifestyle Intervention on Daily Functioning in Older People.

Objective: To investigate the effect of a 2-year multidomain lifestyle intervention on daily functioning of older people.

Design: A 2-year randomized controlled trial (ClinicalTrials.gov, NCT01041989).