Publications by authors named "Pauliina Hietasalo"
Background: In Finland, at least 1 in 4 residents will be >75 years of age in 2030. The national aging policy has emphasized the need to improve supportive services to enable older people to live in their own homes for as long as possible.
Objective: This study aimed to develop a preventive health screening procedure for home-dwelling older adults aged 75 years to enable the use of clinical patient data for purposes of strategic planning of supportive services in primary care.
Background: Poor medication management may negatively impact the health and functional capacity of older adults. This cross-sectional study aimed to identify medication-related risk factors in home-dwelling residents using a validated self-assessment as part of comprehensive health screening.
Methods: The data were derived from comprehensive health screening (PORI75) for older adults of 75 years living in Western Finland in 2020 and 2021.
Objectives: The primary objective of this study is to evaluate the therapeutic potential of hydroxychloroquine (HCQ) in the treatment of adult patients with PCR-confirmed Covid-19 infection in a primary open-care setting, as compared to placebo. The study hypothesis is that treatment with HCQ will reduce the risk of hospitalization because of Covid-19 infection, and the sample size estimate of the study is based on the need to test this hypothesis. The secondary objectives of the study are: to evaluate the safety and tolerability of HCQ in the treatment of adult patients with PCR-confirmed Covid-19 infection in a primary open-care setting, as compared to placebo; to collect experience of the use of HCQ in the treatment of Covid-19 infection in outpatients, in order to be able to identify patient characteristics that predict specific treatment responses (favourable or unfavourable); this objective will also be addressed by post-hoc subgroup analysis of the study results and by meta-analysis of pooled patient data from other clinical trials of HCQ in outpatients; and to evaluate the impact of Covid-19 infection and its treatment on the mental health and well-being of the study participants.
View Article and Find Full Text PDFObjectives: The aim of this study was to determine whether the baseline oral health-related knowledge, attitudes and beliefs of the participants in a randomized clinical trial (RCT) were associated with D(3)MFS increment. Additionally, the aim was to study whether the association was mediated by the two baseline behaviors, i.e.
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- * Participants included 250 in the experimental group who underwent additional caries management and 247 in the control group who received standard care, with follow-up from 2005-2008.
- * Results showed that former experimental group participants had lower treatment costs, better clinical outcomes (measured by DMFS scores), and more regular use of dental services compared to the control group.
The aim of this study was to assess the cost-effectiveness of an experimental caries-control regimen in a randomized clinical trial (RCT) conducted in Pori, Finland, in 2001-2005. Children (n = 497) who were 11-12 yr of age and had at least one active initial caries lesion at baseline were studied. The children in the experimental group (n = 250) were offered an individually designed patient-centered regimen for caries control.
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- - The study in Pori, Finland, aimed to find out if initial oral health behaviors in children could predict later challenges in managing dental caries over a 3.4-year period.
- - A total of 497 children aged 11-12, who had at least one active caries lesion at the start, were analyzed by looking at clinical exams from 2001 to 2005 and a questionnaire about their oral habits.
- - Results showed that brushing teeth with fluoride toothpaste at least twice a day lowered the risk of caries, while daily candy consumption increased the likelihood of developing multiple new caries lesions.