Publications by authors named "Paula Samper-Mateo"

Backround: The aim of our study was to analyze outcomes and safety of laparoscopic simple prostatectomy (LSP) in a high-volume center.

Methods: A consecutive series of men with lower urinary tract symptoms and large prostates (>80 cc) prospectively enrolled between November 2015 and December 2017 in one center. All patients underwent laparoscopic simple prostatectomy.

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Article Synopsis
  • The study investigates the link between anogenital distance (AGD) and the risk of prostate cancer (CaP), aiming to expand on previous research about AGD as an indicator of prenatal androgen levels.
  • A case-control study involved 260 men, where AGD measurements were taken, and the relationship between AGD and CaP was analyzed using various statistical methods.
  • Results indicated that AGD could be a helpful clinical marker for diagnosing CaP, particularly in certain patient subgroups, despite its moderate sensitivity and specificity.
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Article Synopsis
  • The study looked at the connection between how far certain body parts are from each other (anogenital distance) and the risk of prostate cancer in men.
  • Researchers measured this distance in 260 men, some with prostate cancer and some without, to see if it made a difference.
  • They found that men with shorter anogenital distances were more likely to have prostate cancer compared to those with longer distances.
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Article Synopsis
  • - The study evaluated the connection between anogenital distance (AGD), a marker of prenatal androgen exposure, and the severity and prognosis of prostate cancer in 119 patients.
  • - Researchers measured two types of AGD and conducted logistic regression analysis to determine their association with prostate cancer outcomes, focusing on biochemical recurrence and surgical specimen margins.
  • - Results indicate that longer AGD, linked to higher prenatal androgen exposure, correlates with worse prognosis in prostate cancer cases.
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Background: Anogenital distance (AGD), the distance from the centre of the anus to the genitals, is a sexually dimorphic phenotype in mammals. Experimental studies have shown that AGD is a biomarker of prenatal androgen exposure during the masculinisation period of development. The aim of this study is to assess the relationship between anogenital distance (AGD), as an indirect marker of prenatal hormonal environment, and prostate cancer (PCa) severity.

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