Publications by authors named "Paula Quirino"

Article Synopsis
  • - The study focused on Generalized Pustular Psoriasis (GPP), a rare and serious skin condition, examining its course, treatment approaches, and how often patients used healthcare services in Portugal from 2002 to 2023.
  • - It assessed 59 adult patients, revealing that most had a history of another psoriasis type and faced significant health issues, with 64% requiring hospitalization and many experiencing severe symptoms such as fever and high white blood cell counts.
  • - Despite treatment, 98% of patients had at least one flare-up, and only a small number showed improvement by the study's end, indicating a need for better understanding and new treatment options to alleviate the disease's impact.
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Cutaneous mastocytosis is characterized by increased numbers of skin mast cells that release mediators causing pruritus, urticaria, and flushing. Most pediatric mastocytosis patients exhibit the pattern of urticaria pigmentosa, which typically appears during the first two years of life and resolves spontaneously in late adolescence. However, while the disease is active, patients are frequently symptomatic and uncomfortable, which justifies symptomatic treatment.

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