Publications by authors named "Paula Piekoszewska-Zietek"

Patients with genetic syndromes require special dental attention because they have symptoms that promote plaque accumulation, dental erosion, dental caries and gingival diseases. The aim of the study was to assess hygienic behaviors, use of dental care and frequency of professional preventive procedures among Polish children and adolescents with Prader-Willi, Down, Angelman, Silver-Russell and Smith-Lemli-Opitz syndromes. Parents/legal guardians of children and adolescents with genetic syndromes were included.

View Article and Find Full Text PDF

Objectives: Gingivitis manifests as redness, swelling, and bleeding of the gingiva but no loss of connective tissue attachment. It is usually painless and rarely leads to spontaneous bleeding, and most patients are unaware of the disease or are unable to recognize it. In children and adolescents, it is most often caused by plaque accumulation.

View Article and Find Full Text PDF

Background: Preand probiotics may help restore a dysbiotic oral ecosystem. The first years of life provide a window of opportunity to modulate the composition of the oral microbiota and prevent disease.

Objectives: The aim of the present study was to investigate the effect of a tablet containing inactivated Ligilactobacillus salivarius CECT 5317 and the cranberry extract on the development of caries in cariesactive preschool children.

View Article and Find Full Text PDF

Aim: Apart from various typical gastrointestinal symptoms, coeliac disease may have its clinical manifestations in the oral cavity which is the entrance of the gastrointestinal tract.

Methods: A systematic review of literature was performed using the following databases: Medline, Scopus, EBSCOhost and Cochrane Library for Systematic Review.

Inclusion Criteria: observational or experimental original studies published in English with full text available between January 2000 and December 2022, regarding children and adolescents under the age of 20.

View Article and Find Full Text PDF

Introduction: Treatment with glucocorticoids in children with nephrotic syndrome can be the cause of developmental disorders of the masticatory organ and bone or teeth abnormalities. The aim was to assess the frequency and type of dental abnormalities and the correlation of their occurrence with a dosage of glucocorticoids and treatment time in children with idiopathic nephrotic syndrome.

Methods: The study group consisted of 31 patients aged 5 to 17 diagnosed with idiopathic steroid-sensitive nephrotic syndrome and 33 overall healthy children.

View Article and Find Full Text PDF

Carbonic anhydrase (CA) VI is supposed to take part in pH or buffering capacity regulation, which can influence the caries risk of an individual. Its expression in the saliva can be modified by single nucleotide polymorphism (SNP). The aim was to investigate SNP in the CA VI gene in relation to active dental caries and physiochemical properties of saliva.

View Article and Find Full Text PDF

Background: To assess the relationship of chosen salivary proteins and peptides levels with the occurrence of caries in children.

Methods: PubMed, MEDLINE and EMBASE databases from 2000 to 2018 were researched for original observational studies published in English. The risk of bias and quality of the included papers were assessed regarding the guidelines by Fowkes and Fulton.

View Article and Find Full Text PDF

Recent progress in the field of molecular biology and techniques of DNA sequence analysis allowed determining the meaning of hereditary factors of many common human diseases. Studies of genetic mechanisms in the aetiology of caries encompass, primarily, 4 main groups of genes responsible for (1) the development of enamel, (2) formation and composition of saliva, (3) immunological responses, and (4) carbohydrate metabolism. The aim of this study was to present current knowledge about the influence of single nucleotide polymorphism (SNP) genetic variants on the occurrence of dental caries.

View Article and Find Full Text PDF