Publications by authors named "Paula Ormandy"

Introduction: Fluid assessment and management is a key aspect of good dialysis care and is affected by patient-level characteristics and potentially centre-level practices. In this secondary analysis of the BISTRO trial we wished to establish whether centre-level practices with the potential to affect fluid status were stable over the course of the trial and explore if they had any residual associations with participant's fluid status.

Methods: Two surveys (S) of fluid management practices were conducted in 32 participating centres during the trial, (S1: 2017-18 and S2: 2021-22).

View Article and Find Full Text PDF

Background: Preservation of residual kidney function (RKF) in dialysis patients has been associated with improved survival. RKF in the BISTRO trial was relatively well preserved and here we describe its association with survival during the trial and extended follow-up.

Methods: RKF, measured as the average urea and creatinine clearance (GFR) or 24-hour urine volume was assessed at baseline, one, two and three months and three-monthly up to 2 years in incident haemodialysis patients.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluated the economic benefits of using bioimpedance spectroscopy for fluid management in dialysis patients compared to standard methods, focusing on its impact on kidney function and risk of anuria.
  • Conducted in 34 UK dialysis centers, the trial involved 439 adult patients with some residual kidney function, testing how bioimpedance data could optimize patient care.
  • The primary goal was to assess the cost-effectiveness of this approach by calculating the cost per additional quality-adjusted life-year gained over 24 months.
View Article and Find Full Text PDF

Rationale & Objective: Planning and delivering treatment pathways that integrate end-of-life care, frailty assessment, and enhanced supportive care is a service priority. Despite this, people with kidney failure are less likely to have an advance care plan and receive hospice and palliative care compared with other chronic illness populations. This is linked to health professionals feeling unskilled initiating conversations around future treatment and care options.

View Article and Find Full Text PDF
Article Synopsis
  • - This study seeks to better classify individuals with multiple long-term health conditions (MLTCs) by identifying specific clusters of these conditions across various age groups and their links to negative health outcomes and healthcare utilization.
  • - Researchers employed latent class analysis on data from large cohorts, including over 1.8 million individuals, to determine how different MLTC clusters impact mortality, hospital hospitalizations, and general practitioner usage over ten years.
  • - Findings indicated that certain MLTC clusters, particularly those involving cardiometabolic and pain/mental health issues, showed strong associations with higher risks of mortality and healthcare use, particularly in younger and middle-aged individuals, while data from the UKHLS group did not reveal significant risks.
View Article and Find Full Text PDF
Article Synopsis
  • * A total of 42 systematic reviews and 3 additional randomized controlled trials were analyzed, involving nearly 937,000 individuals across 39 LTCs, revealing that exercise improved health-related quality of life (HRQoL) and exercise capacity, though data on mortality and hospitalizations were limited.
  • * The review found methodological quality varied among studies, with a significant number rated as critically low, highlighting the need for more research on multimorbidity and its effects on exercise interventions.
View Article and Find Full Text PDF

Objectives: Cultural and communication differences faced by South-Asian (SA) ethnic minority groups have led to challenges in the delivery of health care and complex management of long-term conditions (LTCs). We aim to explore the use of text-messaging in SA communities, through the Florence (FLO) health messaging system utilised within U.K.

View Article and Find Full Text PDF

Introduction: Personalised Exercise-Rehabilitation FOR people with Multiple long-term conditions (PERFORM) is a research programme that seeks to develop and evaluate a comprehensive exercise-based rehabilitation intervention designed for people with multimorbidity, the presence of multiple long-term conditions (MLTCs). This paper describes the protocol for a randomised trial to assess the feasibility and acceptability of the PERFORM intervention, study design and processes.

Methods And Analysis: A multicentre, parallel two-group randomised trial with individual 2:1 allocation to the PERFORM exercise-based intervention plus usual care (intervention) or usual care alone (control).

View Article and Find Full Text PDF

Background: Depression is common in people with chronic kidney disease, yet little is known about how depression is identified and managed as part of routine kidney care.

Objectives: The primary objective was to survey all UK adult kidney centres to understand how depression is identified and managed. A secondary objective was to broadly describe the variability in psychosocial care.

View Article and Find Full Text PDF

Introduction: In March 2020, a pandemic state was declared due to SARS-COV-2 (COVID-19). Patients with kidney disease, especially those on replacement therapies, proved more susceptible to severe infection. This rapid literature review aims to help understand how the pandemic impacted patient experience of kidney care.

View Article and Find Full Text PDF

Background: Services for patients with kidney disease underwent radical adaptations in response to the COVID-19 pandemic. We undertook an online national survey of UK kidney centres to understand the nature, range, and degree of variation in these changes and to explore factors contributing to differing practice.

Methods: The survey was designed by a multidisciplinary team of kidney professionals, service users and researchers.

View Article and Find Full Text PDF

Background: People living with chronic kidney disease (CKD) need to be able to live well with their condition. The provision of psychosocial interventions (psychological, psychiatric and social care) and physical rehabilitation management is variable across England, as well as the rest of the UK. There is a need for clear recommendations for standards of psychosocial and physical rehabilitation care for people living with CKD, and guidance for the commissioning and measurement of these services.

View Article and Find Full Text PDF

Organ donation continues to be low among ethnic minorities in the United Kingdom (UK), especially within the South Asian community, with a disproportionate number of patients of South Asian ethnicity awaiting organ transplants. In 2020/21, Minority Ethnic (ME) patients comprised almost a third of the national transplant waiting list, highlighting the continued imbalance between the need for transplants in South Asian communities and the availability of suitable organs. Median waiting times for transplants show that, generally, white patients wait less time than ME patients; Only 39.

View Article and Find Full Text PDF
Article Synopsis
  • * In a randomized trial with 439 participants, researchers compared two groups: one using these bioimpedance readings and a control group without.
  • * Results showed no significant difference in RKF decline or blood pressure between groups, indicating that following a standardized fluid assessment protocol suffices for preserving RKF, making bioimpedance measurements unnecessary.
View Article and Find Full Text PDF

Background: Depression is prevalent across the spectrum of Chronic Kidney Disease and associated with poorer outcomes. There is limited evidence regarding the most effective interventions and care pathways for depression in Chronic Kidney Disease.

Objectives: To investigate how depression is identified and managed in adults with Chronic Kidney Disease.

View Article and Find Full Text PDF

The growing older population with advanced chronic kidney disease (ACKD stages 4-5) poses a challenge for healthcare worldwide. The high prevalence of frailty and associated adverse health outcomes highlights concerns for management and interventions specific to this population. The aim was to objectively review the evidence relating to older people (≥65 years) living with frailty and ACKD.

View Article and Find Full Text PDF

Introduction: Patients living with progressive chronic kidney disease may face a variety of ongoing physical, emotional, financial and/or social challenges along the disease pathway. In most UK renal units, psychosocial support has traditionally been provided by a renal social worker. However, in recent years, the numbers of renal social workers have been declining.

View Article and Find Full Text PDF

Objectives: This study used a mixed-method approach to explore cultural and ethnic influences on the perception of, and decision to engage with or not to engage with, physical activity and exercise therapy in patients with chronic kidney disease (CKD).

Design: Qualitative research was conducted through the use of semistructured interviews and focus groups. Self-reported physical activity levels were measured using the General Practice Physical Activity Questionnaire (GPPAQ), and self-efficacy for exercise with Bandura's Self-Efficacy for Exercise Scale.

View Article and Find Full Text PDF

Aims: To explore the employment, work productivity, activity impairment, and sustainability of work of Saudi patients with chronic kidney disease (CKD) on haemodialysis (HD).

Background: Failure to address CKD-related challenges may cause HD patients to lose their job, create a lack of compassion from co-workers and receive discrimination hindering progress in their profession.

Design: This is a cross-sectional explanatory sequential mixed-methods study.

View Article and Find Full Text PDF

Introduction: The number of people with kidney disease using social media to search for medical information and peer support is increasing. IgA nephropathy (IgAN) predominantly affects young adults, demographically the biggest users of social media. This article presents an innovative analysis of social media interactions to identify unmet education and information needs of patients with IgAN.

View Article and Find Full Text PDF

Introduction: Reported outcomes for older people with advanced chronic kidney disease (CKD) often focus on survival and mortality and little attention is paid to symptom burden and health-related quality of life. Recognising frailty and providing interventions that may improve outcomes have been studied in the general population with a growing research interest within CKD.

Methods And Analysis: A scoping review will be undertaken following a recommended process to understand relevant research and priorities for older people living with frailty and advanced CKD.

View Article and Find Full Text PDF

Objective: To examine in-centre haemodialysis patients' emotional distress and need for support across UK renal units with varying models of psychosocial service provision.

Design: The study used a cross-sectional survey design. Logistic regression analysis was used to examine patient distress, as captured by the Distress Thermometer, and need for support, across different renal units.

View Article and Find Full Text PDF

Background: Widespread use of the internet has fundamentally altered the way people access health information and communicate with health providers. Pregnant women are a group who are particularly highly motivated to seek out information online. However, where mothers actually obtain their information, who they trust to supply it, and whether or not it actually fulfils their needs is often unclear.

View Article and Find Full Text PDF

Background: The number of people living with a long-term condition is increasing worldwide. Social media offers opportunities for patients to exchange information and experiences with others with the same condition, potentially leading to better self-management and improved patient outcomes, at minimal costs to health service providers.

Objective: This paper describes how an online network with a range of social media platforms was created, with the help of a group of patients with chronic kidney disease and specialist professionals.

View Article and Find Full Text PDF

Background: Educational taxonomies are utilised within nursing programmes to design curriculum, develop learning objectives, and measure attainments including the assessment of values, behaviours, and attitudes. Current measurement of the affective domain is limited, relying on quantitative tools, often immediately before and after learning activities.

Purpose: This paper examines the reliability of a qualitative framework to assess the long-term impact of learning activities known to stimulate affective domain development.

View Article and Find Full Text PDF