Publications by authors named "Paula Moreno"

We here report on freshwater cave crabs of the families Potamidae and Gecarcinucidae in East Kalimantan, Sarawak, Indonesia in Borneo. A new genus and species of potamid crab, Ngan mayla, is described from Lubang Gedung Cave in the Merabu Karst. With its bullet-shaped eyes, Ngan mayla gen.

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The main limitation to increased rates of lung transplantation (LT) continues to be the availability of suitable donors. At present, the largest source of lung allografts is still donation after the neurologic determination of death (brain-death donors, DBD). However, only 20% of these donors provide acceptable lung allografts for transplantation.

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Article Synopsis
  • Tissue metabolomics provides valuable insights into tissue physiology and tumor characteristics, but obtaining this information is invasive, expensive, and can delay patient care.
  • Computed tomography (CT) is widely used but lacks detailed histological or prognostic information, and integrating metabolomic data with CT for improved classification and prognosis has not been extensively explored.
  • This study introduces a deep learning framework (TMR-CT) that combines CT images with metabolite data, achieving effective histology classification and prognosis in lung cancer patients, outperforming traditional methods and offering a non-invasive alternative to conventional tissue analysis.
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Background: We sought to analyze the influence of lung donor type (brain death [BD] vs controlled donation after cardiac death [DCD]) on lung graft viability and to compare short-term outcomes of lung transplantation using grafts from BD and DCD donors.

Methods: This was a retrospective study of the lung donor population and lung transplants performed at our Institution between January 2020 and December 2022. Demographic characteristics of the donors and donation type (BD vs DCD) were assessed.

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(1) Background: Malignancies are an important cause of mortality after solid organ transplantation. The purpose of this study was to analyze the incidence of malignancies in patients receiving lung transplants (LT) and their influence on patients' survival. (2) Methods: Review of consecutive LT from 1994 to 2021.

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A hydrothermal method was successfully employed to synthesize kesterite CuZnSnS (CZTS) nanoparticles. X-ray diffraction (XRD), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), field-emission scanning electron microscopy (FE-SEM), energy-dispersive X-ray spectroscopy (EDS), transmission electron microscopy (TEM), and optical ultraviolet-visible (UV-vis) spectroscopy were used for characterization of structural, chemical, morphological, and optical properties. XRD results confirmed that a nanocrystalline CZTS phase corresponding to the kesterite structure was formed.

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(1) Objective: To determine whether recent advances in lung transplantation (LT) have reduced the incidence and changed the risk factors for airway complications (AC). (2) Methods: Retrospective analysis of patients receiving a lung transplant between January 2007 and January 2019. An AC was defined as a bronchoscopic abnormality in the airway, either requiring or not requiring an endoscopic or surgical intervention.

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Article Synopsis
  • - Primary ciliary dyskinesia (PCD) is a rare lung disease that can cause permanent lung damage and may lead to respiratory failure, with lung transplant being a possible solution in advanced cases.
  • - This study analyzed data from 36 PCD patients who received lung transplants between 1995 and 2020, focusing on their survival rates and the incidence of lung dysfunction after the transplant.
  • - Overall survival was about 5.9 years, with similar outcomes for patients with and without situs abnormalities; however, those with situs abnormalities had a higher rate of rejection in the first year, highlighting the feasibility and challenges of lung transplantation in PCD patients.
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Early intervention can help children learn language and improve social communication. However, many barriers, including the expense of services and an insufficient number of providers, prohibit families from accessing services when their children are young. We developed a comprehensive online program for caregivers of autistic children.

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Racial disparities exist in autism diagnosis, and yet, the development of most diagnostic tools has not explicitly examined measurement equity between racial and ethnic groups. We examined the validity of the Toddler Autism Symptom Inventory (TASI), a semi-structured interview developed for diagnosis of toddlers, in non-Hispanic Black/African American and non-Hispanic White children. After controlling for group differences in socio-economic status, no differences in diagnosis, age at diagnosis, mean developmental level, or autism severity were found.

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Background: Clinical thermography is a relatively novel technique in wide use in different medical fields because of its versatility and ease of application. It inflicts no pain and entails no contact with the pediatric patient, which assuages anxiety and fear in patients when undergoing diagnostic exploration. The use of infrared clinical thermography being suggested herein is to establish normality patterns, which have not been described in the relevant literature.

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Pulmonary hypertension after surgical correction of D-transposition of the great vessels is a rare but serious complication. Lung transplantation may be the only option when treatment with vasodilators is insufficient. We present the case of a young male patient with a history of arterial switch in neonatal period who undergoes double lung transplantation owing to late pulmonary hypertension.

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Background: This study aims to assess the incidence of primary lung cancer in the native lung and its impact on survival in patients undergoing single lung transplantation (SLT).

Methods: This study retrospectively analyzed 161 SLTs performed between June 2012 and June 2019. The incidence of carcinoma in the native lung and its influence on patient survival was determined.

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Sternal osteomyelitis is a serious complication that significantly increases morbidity and mortality after thoracic surgery. We describe a case of sternal osteomyelitis by Trichosporon inkin following lung transplantation and the excellent results achieved with vacuum-assisted closure therapy.

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NMR offers the unique potential to selectively excite the chosen nuclei avoiding in an extraordinary way the matrix effect. Quantitative Nitrogen-14 NMR (N qNMR) spectroscopy has been introduced for the first time as a robust and validated method to determine choline in a variety of matrixes including quinoa grains, instant coffee and food supplements. A study about the ion pairing of choline bitartrate in aqueous solution by means of diffusion PGSE, NOESY and HOESY NMR have been also provided.

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Objective: To determine whether problems arising in the native lung may influence the short-term outcomes and survival after single lung transplantation (SLT), and therefore should be taken into consideration when selecting the transplant procedure.

Patients And Methods: Retrospective review of 258 lung transplants performed between June 2012 and June 2019. Among them, 161 SLT were selected for the analysis.

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G protein-coupled receptors (GPCRs) are the most common pharmacological target in human clinical practice. To perform their functions, many GPCRs must accumulate inside primary cilia, microtubule-based plasma membrane protrusions working as cellular antennae. Nevertheless, the molecular mechanisms underlying GPCR ciliary targeting remain poorly understood.

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Objective: Lung transplantation (LT) for pulmonary fibrosis is related to higher mortality than other transplant indications. We aim to assess whether the amount of anterior mediastinal fat (AMF) was associated to early and long-term outcomes in fibrotic patients undergoing LT.

Methods: Retrospective analysis of 92 consecutive single lung transplants (SLT) for pulmonary fibrosis over a 10-year period.

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Objectives: The European Society of Thoracic Surgeons Lung Transplantation Working Group promoted a survey to evaluate overall survival in a large cohort of patients receiving lung transplants for rare pulmonary diseases.

Methods: We conducted a retrospective multicentre study. The primary end point was overall survival; secondary end points were survival of patients with the most common diagnoses in the context of rare pulmonary diseases and chronic lung allograft dysfunction (CLAD)-free survival.

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The present study describes a new species of Pyrgoma Leach, 1817, a coral associated barnacle attached to Tubastrea, from the south of New Caledonia. Pyrgoma spurtruncata sp. nov.

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Lung squamous cell carcinoma (LSCC) and adenocarcinoma (LADC) are the most common lung cancer subtypes. Molecular targeted treatments have improved LADC patient survival but are largely ineffective in LSCC. The tumor suppressor FBW7 is commonly mutated or down-regulated in human LSCC, and oncogenic activation combined with inactivation in mice (KF model) caused both LSCC and LADC.

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