A new catalytic mechanism of bacterial ferredoxin-NADP reductases due to a particular NADP binding mode.

Ferredoxin-NADP reductases (FNRs) are ubiquitous flavoenzymes involved in redox metabolisms. FNRs catalyze the reversible electron transfer between NADP(H) and ferredoxin or flavodoxin. They are classified as plant- and mitochondrial-type FNR.