Publications by authors named "Paula Mayo-Gonzalez"
Article Synopsis
- * Deleting Snail1 in CAFs reduced their ability to polarize bone-marrow-derived macrophages (BMDMΦs) towards an immunosuppressive phenotype, compared to those exposed to active CAFs, which inhibited macrophage cytotoxicity.
- * Active CAFs also promoted gene expressions related to immunosuppression in macrophages and the activation of regulatory T cells (T-regs), suggesting that CAFs in the tumor microenvironment hinder anti-tumor immunity. *
