Context: Low T levels have been associated with ejaculatory dysfunction (EjD) in cross-sectional studies; however, the efficacy of T replacement in improving EjD has not been studied in a randomized controlled trial.
Objective: To evaluate the efficacy of T replacement in androgen-deficient men with EjD.
Design: A multicenter, double-blind, randomized, placebo-controlled, 16-week trial with T solution 2% versus placebo.