Publications by authors named "Paula Hammer"

Article Synopsis
  • This study investigated the effectiveness of Anion Exchange Resin (AER) in reducing serum levels of perfluorooctanesulfonic acid (PFOS) in adults exposed to high levels of PFAS.
  • It was a controlled crossover trial with 45 participants, where one group received AER and the other was observed for 12 weeks.
  • Results showed that treatment significantly decreased PFOS levels by a mean of 115 ng/mL (60%), with no serious side effects, indicating AER could be a viable treatment option for PFOS elimination.
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Objective: The aim was to investigate the association between night work during pregnancy and risk of having a small for gestational age (SGA) child.

Methods: This cohort study had payroll data with detailed information on working hours for employees in all Danish administrative regions (primarily hospital employees) between 2007 and 2015, retrieved from the Danish Working Hour Database. Pregnancies, covariates and outcome were identified from the national birth registry.

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Article Synopsis
  • PFAS are man-made chemicals that have been widely used since the 1950s for their water- and grease-repellent properties and resistance to heat.
  • These substances are extremely persistent in the environment and have been linked to various health issues, including immune problems, hormonal disruptions, and certain cancers.
  • The text reviews PFAS pollution in Denmark, focusing on human exposure, potential health effects, and how patients are managed in environmental medicine.
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Introduction: Per- and polyfluoroalkyl substances (PFAS) are persistent chemicals used in many industries and everyday consumer products and exposure has been linked to several adverse health outcomes. Currently, no systematic monitoring of PFAS levels in the general Danish population has been conducted.

Objective: To study temporal trends of PFAS concentrations in the Danish population.

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Background: Pregnancy can make it difficult to cope with demands at work and may affect women's well-being. We investigated if a manager-targeted educational intervention reduced demanding occupational exposures and improved the psychosocial work environment and well-being among pregnant employees.

Methods: Data came from a cluster randomised trial in Danish hospitals and day-care institutions.

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Objective: The aim was to test if targeting managers with an educational intervention reduces absence among pregnant employees.

Methods: The study was a non-blinded cluster randomised trial conducted in hospitals and daycare institutions from two administrative Danish Regions and two Danish municipalities. Clusters (work units) were assigned randomly and non-blinded to either (1) intervention, where all managers were invited to participate in a 3-hour seminar addressing needs and options for adjustment of work in pregnancy, or (2) control, with practice as usual.

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Night work has been associated with sleep disorders as well as cardiovascular, endocrinologic, metabolic and immunological disturbances as shown in this review. Several night shifts in a row and more than one night shift per week is associated with increased risk of pregnancy-related complications. A dose-response pattern has been shown between the number of night shifts during pregnancy and the risk of miscarriage, hypertensive disorders and sick leave.

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Objective We aimed to investigate the association of night work during pregnancy with the risk of severe postpartum depression (PPD). Methods We performed a nationwide register-based cohort study of workers in all Danish public hospitals. Daily information on working hours was retrieved from the Danish Working Hour Database from January 2007 to December 2015.

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Background: Melatonin stimulates the production of progesterone, which is essential for the maintenance of pregnancy. Since melatonin in blood is reduced due to work under illuminated conditions during night work, it has been hypothesized that night work may increase the risk of preterm birth. Previous meta-analyses have not revealed increased risk of preterm birth in women working night shifts during pregnancy.

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Objective: Observational studies indicate an association between working nights and miscarriage, but inaccurate exposure assessment precludes causal inference. Using payroll data with exact and prospective measurement of night work, the objective was to investigate whether working night shifts during pregnancy increases the risk of miscarriage.

Methods: A cohort of 22 744 pregnant women was identified by linking the Danish Working Hour Database (DWHD), which holds payroll data on all Danish public hospital employees, with Danish national registers on births and admissions to hospitals (miscarriage).

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Objective: The aim of our study was to investigate the acute effect of night work during pregnancy on the risk of calling in sick the following day using register-based information and the workers as their own controls.

Methods: Using the payroll-based national Danish Working Hour Database, including all public hospital employees in Denmark, we identified 9799 pregnant women with ≥1 day shift and ≥1 night shift and ≥1 day of sick leave during the first 32 pregnancy weeks from January 2007 to December 2013. We performed fixed effects logistic regression, that is, within-worker comparisons, of the risk of sick leave of any duration starting within 24 hours after night shifts of different length versus day shifts.

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Objective The aim of this study was to investigate whether night work expressed by number and duration of night shifts, number of consecutive night shifts, and number of quick returns during the first 20 weeks of pregnancy is a risk factor for hypertensive disorders of pregnancy (HDP). Methods The study population comprised Danish workers in public administration and hospitals who gave birth between 2007 and 2013. Exposure was assessed objectively through payroll data.

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Objective: We systematically reviewed the epidemiologic evidence linking finger and wrist osteoarthritis (OA) with work activities requiring pinch or hand grip or exposure to hand-arm vibration (HAV).

Methods: PubMed and Embase databases were searched up to June 2013. We selected studies assessing the associations of radiographic diagnosed finger and/or wrist joint OA with work activities involving pinch or hand grip or exposure to HAV.

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