Publications by authors named "Paula Gabriela Sousa de Oliveira"
Non-Hodgkin's Lymphoma (NHL) is a malignancy of the lymphoid lineage of the hematopoietic system has worldwide, especially in developed countries. Better diagnostic and recording techniques, longer life expectancy, and greater exposure to risk factors are hypotheses for this growing incidence curve. Occupational exposures to chemical, biological, and physical agents have also been associated with NHL development, but the results are still controversial.
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- Acute kidney injury (AKI) frequently occurs in hospitalized COVID-19 patients in Brazil, with a notable incidence of 46.4%, particularly in those in intensive care units (68.1%).
- Key risk factors for developing AKI include older age, mechanical ventilation, presence of proteinuria, and use of vasoactive drugs.
- Mortality rates were significantly higher among patients with AKI (36.1%), especially among the elderly and those requiring mechanical ventilation, indicating that AKI is a serious complication associated with COVID-19.
Background: In the absence of direct therapy for COVID-19, extracorporeal blood treatment (EBT) could represent an option for cytokine removal.
Objective: This study aimed to describe and compare cytokine removal during intermittent haemodialysis (IHD) and continuous renal replacement therapy (CRRT) in COVID-19 patients with Acute Kidney Injury (AKI).
Methods: It was a cohort study that studied patients with COVID-19-related AKI according to KDIGO criteria and admitted at Intensive Care Unit (ICU).
Article Synopsis
- Elderly patients (median age 72) with COVID-19 are at increased risk for acute kidney injury (AKI), which is linked to worse outcomes, particularly in individuals with comorbidities like hypertension.
- A study examining 347 COVID-19 patients in a public hospital found that 56.9% of elderly patients developed AKI, especially those in the ICU, with significant morbidity requiring kidney replacement therapy.
- Key risk factors for AKI included higher baseline creatinine levels and the need for mechanical ventilation, with mortality rates being significantly higher in patients with AKI (46.41% vs. 24.7%).
Renal involvement is frequent in COVID-19 (4-37%). This study evaluated the incidence and risk factors of acute kidney injury (AKI) in hospitalized patients with COVID-19. This study represents a prospective cohort in a public and tertiary university hospital in São Paulo, Brazil, during the first 90 days of the COVID-19 pandemic, with patients followed up until the clinical outcome (discharge or death).
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