Publications by authors named "Paula G Barreto"
Objectives: Quantitative analysis of the implementation of the bedside paediatric early warning system (B-PEWS) in a resource-limited setting. The B-PEWS serves to pre-emptively identify hospitalised children who are at risk for cardiopulmonary arrest and subsequently to provide critical care in time.
Methods: We performed a retrospective review through the medical data records of patients after discharge from the paediatric ward of a philanthropic hospital in Brazil.
Background: Merkel cell carcinoma (MCC) is a rare but aggressive primary cutaneous carcinoma with high mortality rates. The present study intends to delineate the epidemiological profile of patients with MCC seen at the Clinics Hospital of the Medical School at the University of São Paulo, Brazil, and its association with Merkel cell polyomavirus (MCPyV).
Methods: This is a retrospective study.
Background: Rotaviruses can cause life-threatening health disorders, such as severe dehydrating gastroenteritis and diarrhea in children. Vaccination is the main preventive strategy to reduce rotavirus diarrhea and the severity of episodes, but vaccines are not fully effective and new episodes may occur, even in vaccinated children. The WHO recommends oral rehydration therapy and zinc supplementation for rotavirus-induced diarrhea management.
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- The study investigates the hypothesis that essential tremor (ET) may be related to hyperactivity in the posterior putamen, contrasting traditional views that focus on the olivocerebellar system.
- A rat model of ET was used, with groups undergoing either surgery to remove sections of the posterior striatum or sham procedures, followed by administration of harmaline to induce tremors for assessment.
- Results showed significant tremor reduction in the experimental group that had surgery, suggesting the posterior striatum's involvement in ET and supporting the proposed hypothesis.