Publications by authors named "Paula Franca"

A competitive volleyball game is a highly metabolic and physically demanding event for professional players. This study aimed to investigate whether a single game at the end of a preseason promotes changes in the biochemical markers of physical exercise responses and the metabolomic profile of professional volleyball players. This cross-sectional study included 13 male Brazilian professional volleyball players.

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The nutrient composition of plant-based burgers is a key factor when making their purchase/consumption decision to maintain a balanced diet. For this reason, ingredient list and nutritional information of burgers launched in the global market were retrieved from their labels. Products were classified based on the technology development, market position and region of the manufacturer.

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Article Synopsis
  • * Two groups of women participated: one received laser therapy combined with muscle strengthening exercises, while the other only performed exercises without laser treatment (placebo).
  • * Results showed that the group receiving laser therapy significantly improved their quality of life, muscle strength, and endurance compared to the placebo group, suggesting that this treatment method is beneficial for pelvic floor dysfunction.
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  • The rise of antimicrobial resistance highlights the urgent need for new antimicrobial agents, with Actinobacteria, especially the Streptomyces genus, being key producers of antibiotics and anti-cancer drugs.
  • This study identified Streptomyces albidoflavus ANT_B131 from Antarctica, which showed effective antimicrobial and antiproliferative activities against various pathogens and human tumor cell lines.
  • Whole-genome sequencing revealed 24 biosynthetic gene clusters (BGCs) in the bacterium, with the use of different culture media and extraction methods leading to a better expression and recovery of these natural products.
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Adolescent athletes require adequate energy and nutrient supply to support growth, development, and the demands associated with exercise and training. However, they are susceptible to nutritional inadequacies affecting their health and physical performance. Food choices with nutrient adequacy and environmental protection is crucial for a sustainable diet.

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Reflectance confocal microscopy (RCM) with endogenous backscattered contrast can noninvasively image basal cell carcinomas (BCCs) in skin. However, BCCs present with high nuclear density, and the relatively weak backscattering from nuclei imposes a fundamental limit on contrast, detectability, and diagnostic accuracy. We investigated PARPi-FL, an exogenous nuclear poly(adenosine diphosphate ribose) polymerase (PARP1)-targeted fluorescent contrast agent, and fluorescence confocal microscopy toward improving BCC diagnosis.

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Purpose: We performed a first-in-human clinical trial. The aim of this study was to determine safety and feasibility of PET imaging with F-PARPi in patients with head and neck cancer.

Patients And Methods: Eleven patients with newly diagnosed or recurrent oral and oropharyngeal cancer were injected with F-PARPi (331 ± 42 MBq), and dynamic PET/CT imaging was performed between 0 and 25 minutes postinjection.

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sp. strain ANT_B65 was isolated from sponge collected in King George Island, Antarctica. The draft genome of 4,173,840 bp encodes 3,743 protein-coding open reading frames.

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Linear alkylbenzene sulfonate (LAS) is widely used in the formulation of domestic and industrial cleaning products, the most synthetic surfactants used worldwide. These products can reach water bodies through the discharge of untreated sewage or non-effective treatments. This study evaluates the ability of the microorganisms found in the Tiete river sediment to degrade this synthetic surfactant.

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