Functional Divergence of the bag-of-marbles Gene in the Drosophila melanogaster Species Group.

In Drosophila melanogaster, a key germline stem cell (GSC) differentiation factor, bag of marbles (bam) shows rapid bursts of amino acid fixations between sibling species D. melanogaster and Drosophila simulans, but not in the outgroup species Drosophila ananassae. Here, we test the null hypothesis that bam's differentiation function is conserved between D.

Diverse wMel variants of Wolbachia pipientis differentially rescue fertility and cytological defects of the bag of marbles partial loss of function mutation in Drosophila melanogaster.

In Drosophila melanogaster, the maternally inherited endosymbiont Wolbachia pipientis interacts with germline stem cell genes during oogenesis. One such gene, bag of marbles (bam) is the key switch for differentiation and also shows signals of adaptive evolution for protein diversification. These observations have led us to hypothesize that W.

Digest: No conflict of interest between the sexes for optimal immune response in threespine stickleback.

Will sex-specificparasite exposure lead to sexually antagonistic immune trait fitness optima? Despite female stickleback encountering parasites at a higher rate, De Lisle and Bolnick found no evidence of sexual conflict related to their primary immune trait. Both male and female fish suffered high costs of infection and immune response on reproduction. If costs of both immunity and infection are high and concordant, the sexual conflict will not arise despite different parasite exposure rates.