We present here a case of a newborn presenting with a vesicular rash on the scalp and thorax on day 9 of life. Vesicular fluid polymerase chain reaction testing confirmed the presence of Mpox virus DNA. Similar reports in newborns are rare, and we suggest that Mpox infection should be considered in the differential diagnosis of a neonatal vesicular rash, particularly if there is a history of similar rashes in the family.
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