Sirolimus Associated with Tacrolimus at Low Doses in Elderly Kidney Transplant Patients: A Prospective Randomized Controlled Trial.

Objectives: There is no consensus on the best immunosuppressive regimen for elderly renal transplant recipients. The objective of this study was to assess cytomegalovirus infection incidence and kidney transplant outcomes in elderly recipients treated with mammalian target of rapamycin inhibitors sirolimus/ tacrolimus at low doses compared with those receiving tacrolimus/mycophenolate sodium.

Materials And Methods: In this single-center prospective randomized study (Trial Registration No.

Randomized Trial of Machine Perfusion Versus Cold Storage in Recipients of Deceased Donor Kidney Transplants With High Incidence of Delayed Graft Function.

Background: This study compared the use of static cold storage versus continuous hypothermic machine perfusion in a cohort of kidney transplant recipients at high risk for delayed graft function (DGF).

Methods: In this national, multicenter, and controlled trial, 80 pairs of kidneys recovered from brain-dead deceased donors were randomized to cold storage or machine perfusion, transplanted, and followed up for 12 months. The primary endpoint was the incidence of DGF.

A case report of venous thrombosis after kidney transplantation - We can save the graft? Time is the success factor.

Introduction: Venous thrombosis is a serious surgical complication that frequently results in loss of kidney graft.

Case Presentation: We report the case of a female patient recipient of a decease kidney transplant that in the tenth postoperative presented with hematuria, graft pain and oliguria. Ultrasound examination was suggestive of venous thrombosis with abnormal doppler waveform pattern and reversal of diastolic flow.

Emphysematous pyelonephritis in a transplanted kidney.

Emphysematous pyelonephritis is a rare infection characterized by necrosis and gas accumulation in the renal parenchyma, adjacent tissues, and/or urinary collecting system. This entity is rarely reported in transplanted kidneys. Computed tomography imaging is necessary for diagnosis and risk classification.

Behavioral measures to reduce non-adherence in renal transplant recipients: a prospective randomized controlled trial.

Purpose: Solid-organ transplant recipients present a high rate of non-adherence to drug treatment. Few interventional studies have included approaches aimed at increasing adherence. The objective of this study was to evaluate the impact of an educational and behavioral strategy on treatment adherence of kidney transplant recipients.

Different induction therapies for kidney transplantation with living donor.

Introduction: Indications for induction therapy is not consensual in living donors.

Objective: The objective of this study was compare no induction with thymoglobulin and basiliximab induction in the incidence of acute rejection in kidney transplantation with living donor.

Methods: We select all cases of renal transplantation with living donor performed in Hospital das Clínicas de Botucatu da UNESP during the period of January 2010 to December 2013.

Quantified power Doppler as a predictor of delayed graft function after renal transplantation.

Purpose: No safe ultrasound (US) parameters have been established to differentiate the causes of graft dysfunction.

Objectives: To define US parameters and identify the predictors of normal graft evolution, delayed graft function (DGF), and rejection at the early period after kidney transplantation.

Methods: Between June 2012 and August 2013, 79 renal transplant recipients underwent US examination 1-3 days posttransplantation.

The 600 kidney transplants performed at the Botucatu Medical School Hospital - UNESP: changes over.

Introduction: A progressive improvement in kidney transplant outcomes has been achieved over the last decades.

Objective: To determine the degree to which this has occurred in our center, we conducted an outcome analysis of our kidney transplant program during three different time periods, especially focusing on patient and graft survival.

Methods: The 600 kidney transplants performed at Botucatu Medical School/UNESP up to December 2011 were examined.

Coronary artery disease treatment in dialysis patients at the Hospital das Clínicas da Faculdade de Medicina de Botucatu--UNESP.

Background: Interventional treatment of coronary insufficiency is underemployed among dialysis patients. Studies confirming its efficacy in this set of patients are scarce.

Objective: To assess the results of interventional treatment of coronary artery disease in patients undergoing dialysis.